Diphenylether

Diphenylether

SCHEMBL2009809

C=C(C)C(=O)OCCOCCO.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.49
POLB P06746 1/20 0.44
APEX1 P27695 1/20 0.44
HTT P42858 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ELANE P08246 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
FFAR1 O14842 1/20 0.39
ALDH1A1 P00352 1/20 0.39
RECQL P46063 1/20 0.39
NPC1 O15118 1/20 0.38
HPGD P15428 1/20 0.38
CRHBP P24387 1/20 0.38
RAB9A P51151 1/20 0.38
CRHR2 Q13324 1/20 0.38
GALR3 O60755 1/20 0.37
TSHR P16473 2/20 0.37
MMP2 P08253 1/20 0.37
MMP9 P14780 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylether SCHEMBL8065399 0.91 POLB (0.48) THRBPOLBAPEX1HTTTDP1
Phthalic Acid SCHEMBL11648033 0.86 THRB (0.49) THRBPOLBAPEX1HTTTDP1
Phthalic Acid SCHEMBL5416343 0.86 THRB (0.49) THRBPOLBAPEX1HTTTDP1
Diphenylether SCHEMBL8584305 0.85 ALDH1A1 (0.43) FFAR1ALDH1A1RECQLNPC1HPGD
Diphenylether SCHEMBL19064985 0.85 ALDH1A1 (0.48) FFAR1ALDH1A1RECQLHPGDGALR3
SCHEMBL1173746 0.84 POLB (0.57) THRBPOLBAPEX1HTTTDP1
SCHEMBL437611 0.84 POLB (0.57) THRBPOLBAPEX1HTTTDP1
SCHEMBL910146 0.84 POLB (0.57) THRBPOLBAPEX1HTTTDP1
SCHEMBL1524479 0.84 POLB (0.57) THRBPOLBAPEX1HTTTDP1
SCHEMBL1524744 0.84 POLB (0.57) THRBPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7964683-B2 Biocompatible polymeric compound, biocompatible polymer and polymer particles FUJIFILM CORPORATION (JP) 2011-06-21 US disclosed
US-20100016534-A1 BIOCOMPATIBLE POLYMERIC COMPOUND, BIOCOMPATIBLE POLYMER AND POLYMER PARTICLES FUJIFILM CORPORATION (JP) 2010-01-21 US disclosed
US-20090246653-A1 RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING, RELIEF PRINTING PLATE, AND METHOD OF MANUFACTURING RELIEF PRINTING PLATE FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100016534-A1 BIOCOMPATIBLE POLYMERIC COMPOUND, BIOCOMPATIBLE POLYMER AND POLYMER PARTICLES CD68, ARG1, PUF60 THRB 4311/4885POLB 3843/4885APEX1 2025/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.