SCHEMBL16142

SCHEMBL16142

C=C(C)C(=O)OCCCCCCCCCCOP(=O)(O)OCCCCCCCCCCOC(=O)C(=C)C

nearest known ligand 0.62

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.62
POLB P06746 1/20 0.48
APEX1 P27695 1/20 0.48
HTT P42858 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
THRB P10828 1/20 0.46
LPAR3 Q9UBY5 4/20 0.40
LPAR2 Q9HBW0 3/20 0.40
LPAR1 Q92633 2/20 0.40
ALDH1A1 P00352 2/20 0.40
BTN3A1 O00481 1/20 0.40
P2RY10 O00398 4/20 0.38
GPR34 Q9UPC5 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL346466 1.00 TSHR (0.62) TSHRPOLBAPEX1HTTTDP1
SCHEMBL15881 1.00 TSHR (0.62) TSHRPOLBAPEX1HTTTDP1
SCHEMBL15172 1.00 TSHR (0.62) TSHRPOLBAPEX1HTTTDP1
SCHEMBL3447377 1.00 TSHR (0.62) TSHRPOLBAPEX1HTTTDP1
SCHEMBL7073886 1.00 TSHR (0.62) TSHRPOLBAPEX1HTTTDP1
SCHEMBL3447994 1.00 TSHR (0.62) TSHRPOLBAPEX1HTTTDP1
Ammonia Solution, Strong SCHEMBL18139905 0.98 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL345781 0.98 TSHR (0.59) TSHRPOLBAPEX1HTTTDP1
Ammonia Solution, Strong SCHEMBL18140012 0.96 TSHR (0.58) TSHRPOLBAPEX1HTTTDP1
SCHEMBL15412 0.95 TSHR (0.55) TSHRPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 627 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118879207-A High temperature resistant acrylate adhesives 伊利诺斯工具制品有限公司 2024-11-01 CN claimed
US-20240279516-A1 HIGH TEMPERATURE RESISTANT ACRYLIC ADHESIVE ILLINOIS TOOL WORKS INC. (US) 2024-08-22 US claimed
EP-4035647-B1 TWO-COMPONENT SELF-ADHESIVE DENTAL COMPOSITION, PROCESS OF PRODUCTION AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-10-18 EP claimed
EP-4035647-A1 TWO-COMPONENT SELF-ADHESIVE DENTAL COMPOSITION, PROCESS OF PRODUCTION AND USE THEREOF 3M Innovative Properties Company (US) 2022-08-03 EP claimed
EP-2492289-B1 POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL KURARAY NORITAKE DENTAL INC (JP) 2020-03-18 EP claimed
EP-2628476-B1 FILLER CONTAINING COMPOSITION AND PROCESS FOR PRODUCTION AND USE THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2018-03-28 EP claimed
EP-2628476-A1 Filler containing Composition and Process for Production and Use thereof 3M Innovative Properties Company (US) 2013-08-21 EP claimed
CN-118879207-A High temperature resistant acrylate adhesives 伊利诺斯工具制品有限公司 2024-11-01 CN disclosed
US-20240279516-A1 HIGH TEMPERATURE RESISTANT ACRYLIC ADHESIVE ILLINOIS TOOL WORKS INC. (US) 2024-08-22 US disclosed
EP-4056144-B1 DENTAL ARTICLES, METHODS, AND KITS INCLUDING A COMPRESSIBLE MATERIAL SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-07-10 EP disclosed
US-12030970-B2 Curable composition and stereolithographic resin composition comprising same KURARAY CO., LTD. (JP) 2024-07-09 US disclosed
US-20240216228-A1 CALCIUM AND FLUORINE IONS RELEASING DENTAL COMPOSITION SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2024-07-04 US disclosed
WO-2024134298-A1 CURABLE PRECURSOR OF A COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-06-27 WO disclosed
US-5364918-A Surface modification of polymer objects BAUSCH & LOMB INCORPORATED (US) 1994-11-15 US disclosed
EP-0559820-A1 SURFACE COATING OF POLYMER OBJECTS BAUSCH & LOMB INCORPORATED (US) 1993-09-15 EP disclosed
EP-0559809-A1 SURFACE MODIFICATION OF POLYMER OBJECTS. BAUSCH & LOMB (US) 1993-09-15 EP disclosed
US-5219965-A Adding polymerizable surfactant to monomer mixture; contact lenses BAUSCH & LOMB INCORPORATED (US) 1993-06-15 US disclosed
US-5135297-A Immersing a contact lens in an aqueous dispersion of a polymerizable surfactant macromer, a crosslinker and a free radical catalyst and irradiating with UV light; wetting agents BAUSCH & LOMB INCORPORATED (US) 1992-08-04 US disclosed
WO-1992009650-A1 SURFACE COATING OF POLYMER OBJECTS BAUSCH & LOMB INCORPORATED (US) 1992-06-11 WO disclosed
WO-1992009644-A1 SURFACE MODIFICATION OF POLYMER OBJECTS BAUSCH & LOMB INCORPORATED (US) 1992-06-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240216228-A1 CALCIUM AND FLUORINE IONS RELEASING DENTAL COMPOSITION ORAI1, CA3, CHERP TSHR 2815/4885POLB 1239/4885APEX1 2927/4885
US-12030970-B2 Curable composition and stereolithographic resin composition comprising same ARL1, ASH2L, VCL TSHR 4710/4885POLB 2634/4885APEX1 3037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.