SCHEMBL346466

SCHEMBL346466

C=C(C)C(=O)OCCCCCCCCCOP(=O)(O)OCCCCCCCCCOC(=O)C(=C)C

nearest known ligand 0.62

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.62
POLB P06746 1/20 0.48
APEX1 P27695 1/20 0.48
HTT P42858 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
THRB P10828 1/20 0.46
LPAR3 Q9UBY5 4/20 0.40
LPAR2 Q9HBW0 3/20 0.40
LPAR1 Q92633 2/20 0.40
ALDH1A1 P00352 2/20 0.40
BTN3A1 O00481 1/20 0.40
P2RY10 O00398 4/20 0.38
GPR34 Q9UPC5 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16142 1.00 TSHR (0.62) TSHRPOLBAPEX1HTTTDP1
SCHEMBL15881 1.00 TSHR (0.62) TSHRPOLBAPEX1HTTTDP1
SCHEMBL15172 1.00 TSHR (0.62) TSHRPOLBAPEX1HTTTDP1
SCHEMBL3447377 1.00 TSHR (0.62) TSHRPOLBAPEX1HTTTDP1
SCHEMBL7073886 1.00 TSHR (0.62) TSHRPOLBAPEX1HTTTDP1
SCHEMBL3447994 1.00 TSHR (0.62) TSHRPOLBAPEX1HTTTDP1
Ammonia Solution, Strong SCHEMBL18139905 0.98 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL345781 0.98 TSHR (0.59) TSHRPOLBAPEX1HTTTDP1
Ammonia Solution, Strong SCHEMBL18140012 0.96 TSHR (0.58) TSHRPOLBAPEX1HTTTDP1
SCHEMBL15412 0.95 TSHR (0.55) TSHRPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2492289-B1 POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL KURARAY NORITAKE DENTAL INC (JP) 2020-03-18 EP claimed
WO-2024043291-A1 DENTAL ADHESIVE COMPOSITION クラレノリタケデンタル株式会社 2024-02-29 WO disclosed
EP-3936109-B1 SOLVENT-FREE ADHESIVE COMPOSITION FOR DENTAL USE KURARAY NORITAKE DENTAL INC (JP) 2024-02-14 EP disclosed
EP-2979679-B1 CURABLE COMPOSITION FOR DENTAL USE KURARAY NORITAKE DENTAL INC (JP) 2023-11-29 EP disclosed
US-11744782-B2 Separately packed curable composition MITSUI CHEMICALS, INC. (JP) 2023-09-05 US disclosed
US-20230270630-A1 COMPOSITION FOR DENTAL ATTACHMENT KURARAY NORITAKE DENTAL INC. (JP) 2023-08-31 US disclosed
US-20230242681-A1 POLYMERIZATION INITIATOR, KIT FOR PREPARING CURABLE COMPOSITION, CURABLE COMPOSITION, CURED PRODUCT, AND DENTAL MATERIAL MITSUI CHEMICALS, INC. (JP) 2023-08-03 US disclosed
US-20230240947-A1 DENTAL ADHESIVE COMPOSITION AND DENTAL MATERIAL MITSUI CHEMICAIS, INC. (JP) 2023-08-03 US disclosed
EP-4193985-A1 COMPOSITION FOR DENTAL ATTACHMENT Kuraray Noritake Dental Inc. (JP) 2023-06-14 EP disclosed
EP-4166578-A1 POLYMERIZATION INITIATOR, KIT FOR PREPARING CURABLE COMPOSITION, CURABLE COMPOSITION, CURED PRODUCT, AND DENTAL MATERIAL Mitsui Chemicals, Inc. (JP) 2023-04-19 EP disclosed
EP-1269968-B1 Dental cement composition KURARAY CO (JP) 2005-10-12 EP disclosed
EP-1550428-A1 DENTAL COATING KIT Kuraray Medical Inc. (JP) 2005-07-06 EP disclosed
EP-1269967-B1 Dental composition kit KURARAY CO (JP) 2005-05-18 EP disclosed
US-6869984-B2 Dental composition kit KURARAY CO., LTD. (JP) 2005-03-22 US disclosed
US-20030083398-A1 Dental composition kit KURARAY CO. LTD. (JP) 2003-05-01 US disclosed
US-20030064102-A1 Antimicrobial Composition NAKATSUKA KAZUMITSU (JP) 2003-04-03 US disclosed
US-20030055123-A1 Dental cement composition KURARAY CO. LTD, (JP) 2003-03-20 US disclosed
EP-1285947-A1 ANTIMICROBIAL COMPOSITION KURARAY CO., LTD. (JP) 2003-02-26 EP disclosed
EP-1269967-A1 Dental composition kit KURARAY CO., LTD. (JP) 2003-01-02 EP disclosed
EP-1269968-A1 Dental cement composition KURARAY CO., LTD. (JP) 2003-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230270630-A1 COMPOSITION FOR DENTAL ATTACHMENT ITGA1, ITGA2, PPA1 TSHR 4298/4885POLB 2433/4885APEX1 194/4885
US-20230242681-A1 POLYMERIZATION INITIATOR, KIT FOR PREPARING CURABLE COMPOSITION, CURABLE COMPOSITION, CURED PRODUCT, AND DENTAL MATERIAL KIT, SETDB1, NOD1 TSHR 4406/4885POLB 1650/4885APEX1 4044/4885
US-20030064102-A1 Antimicrobial Composition AAAS, H1-0, H1-10 TSHR 4699/4885POLB 149/4885APEX1 890/4885
US-20230240947-A1 DENTAL ADHESIVE COMPOSITION AND DENTAL MATERIAL CAD, CDH1, ITGA1 TSHR 4532/4885POLB 2751/4885APEX1 1414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.