Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.37 |
| ▸ | P2RY10 | O00398 | 4/20 | 0.36 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15172 | 0.98 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL15881 | 0.98 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3447377 | 0.98 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| Ammonia Solution, Strong SCHEMBL18140012 | 0.98 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL7073886 | 0.98 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL346466 | 0.98 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16142 | 0.98 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3447994 | 0.98 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| Ammonia Solution, Strong SCHEMBL18139905 | 0.96 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL15412 | 0.96 | TSHR (0.55) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2492289-B1 | POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL | KURARAY NORITAKE DENTAL INC (JP) | 2020-03-18 | — | — | EP | claimed |
| JP-4746543-B2 | — | — | 2011-08-10 | — | — | JP | claimed |
| US-7700668-B2 | Adhesive composition with decreased polarity upon polymerization | 3M ESPE AG (DE) | 2010-04-20 | — | — | US | claimed |
| US-20060270751-A1 | Adhesive composition with decreased polarity upon polymerization | 3M DEUTSCHLAND GMBH (DE) | 2006-11-30 | — | — | US | claimed |
| EP-1498098-B1 | Adhesive composition with decreased polarity upon polymerization | 3M ESPE AG (DE) | 2006-05-03 | — | — | EP | claimed |
| WO-2005004819-A1 | ADHESIVE COMPOSITION WITH DECREASED POLARITY UPON POLYMERIZATION | 3M ESPE AG (DE) | 2005-01-20 | — | — | WO | claimed |
| EP-1498098-A1 | Adhesive composition with decreased polarity upon polymerization | 3M ESPE AG (DE) | 2005-01-19 | — | — | EP | claimed |
| CN-118240176-A | Polymer, aqueous polymer dispersion and use thereof in coating compositions | PPG涂料(天津)有限公司 | 2024-06-25 | — | — | CN | disclosed |
| WO-2024053223-A1 | CARIOUS TOOTH STRUCTURE RECOVERY AGENT, AND DENTAL ADHESIVE KIT | クラレノリタケデンタル株式会社 | 2024-03-14 | — | — | WO | disclosed |
| EP-3936109-B1 | SOLVENT-FREE ADHESIVE COMPOSITION FOR DENTAL USE | KURARAY NORITAKE DENTAL INC (JP) | 2024-02-14 | — | — | EP | disclosed |
| EP-2979679-B1 | CURABLE COMPOSITION FOR DENTAL USE | KURARAY NORITAKE DENTAL INC (JP) | 2023-11-29 | — | — | EP | disclosed |
| US-11744782-B2 | Separately packed curable composition | MITSUI CHEMICALS, INC. (JP) | 2023-09-05 | — | — | US | disclosed |
| US-20230270630-A1 | COMPOSITION FOR DENTAL ATTACHMENT | KURARAY NORITAKE DENTAL INC. (JP) | 2023-08-31 | — | — | US | disclosed |
| EP-1269967-A1 | Dental composition kit | KURARAY CO., LTD. (JP) | 2003-01-02 | — | — | EP | disclosed |
| EP-1269968-A1 | Dental cement composition | KURARAY CO., LTD. (JP) | 2003-01-02 | — | — | EP | disclosed |
| EP-0740214-B1 | Photosensitive composition and photosensitive rubber plate | ZEON CORP (JP) | 2002-07-10 | — | — | EP | disclosed |
| US-5863704-A | BLENDS OF DIENE-AROMATIC VINYL COPOLYMER BLOCKS, PHOTOPOLYMERIZABLE ETHYLENICALLY UNSATURATED MONOMER AND PHOTOINITIATOR | NIPPON ZEON COMPANY, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| US-5679485-A | CURABLE ELASTIC BLEND CONTAINING HYDROPHOBIC ADDITION POLYMER HAVING PENDANT HYDROPHILIC PHOSPHATE GROUPS; AQUEOUS DEVELOPMENT OF IMAGE | NIPPON ZEON CO., LTD. (JP) | 1997-10-21 | — | — | US | disclosed |
| EP-0751433-A2 | Release composition and photosensitive rubber plate with layer of the same | NIPPON ZEON CO., LTD. (JP) | 1997-01-02 | — | — | EP | disclosed |
| EP-0740214-A2 | Photosensitive composition and photosensitive rubber plate | NIPPON ZEON CO., LTD. (JP) | 1996-10-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230270630-A1 | COMPOSITION FOR DENTAL ATTACHMENT | ITGA1, ITGA2, PPA1 | TSHR 4298/4885THRB 3836/4885POLB 2433/4885 |
| US-20060270751-A1 | Adhesive composition with decreased polarity upon polymerization | PTK2, PHOSPHO1, ITGA1 | TSHR 4650/4885THRB 3495/4885POLB 868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.