Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL238953 | 0.89 | THRB (0.70) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| Alcohol SCHEMBL7030010 | 0.85 | ALDH1A1 (0.68) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL14130577 | 0.85 | ALDH1A1 (0.67) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL28543752 | 0.85 | THRB (0.70) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL16142139 | 0.85 | MAPK1 (0.54) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL9626547 | 0.85 | THRB (0.57) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL39816 | 0.84 | THRB (0.74) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| Acrylic Acid SCHEMBL17101615 | 0.84 | THRB (0.64) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| Ethylene Glycol SCHEMBL10426882 | 0.84 | ALDH1A1 (0.66) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| Acrylic Acid SCHEMBL18580288 | 0.84 | THRB (0.64) | THRBALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170143639-A1 | NANOCOMPOSITES OF GOLD AND POLYMERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-05-25 | — | — | US | disclosed |
| US-20150272900-A1 | Layer-By-Layer Approach to Co-Deliver DNA and siRNA via AuNPs: A Potential Platform for Modifying Release Kinetics | THE JOHNS HOPKINS UNIVERSITY | 2015-10-01 | — | — | US | disclosed |
| US-20140294909-A1 | NANOCOMPOSITES OF GOLD AND POLYMERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150272900-A1 | Layer-By-Layer Approach to Co-Deliver DNA and siRNA via AuNPs: A Potential Platform for Modifying Release Kinetics | DNMT3L, DBNL, HNRNPL | THRB 3106/4885ALDH1A1 2087/4885TP53 892/4885 |
| US-20170143639-A1 | NANOCOMPOSITES OF GOLD AND POLYMERS | HNRNPL, HNRNPLL, ACSL3 | THRB 2303/4885ALDH1A1 883/4885TP53 1592/4885 |
| US-20140294909-A1 | NANOCOMPOSITES OF GOLD AND POLYMERS | HNRNPL, HNRNPLL, ACSL3 | THRB 2303/4885ALDH1A1 883/4885TP53 1592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.