SCHEMBL14130577

SCHEMBL14130577

C=CC(=O)OCC(CC)(CC)COC(=O)C=C

nearest known ligand 0.67

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.67
TP53 P04637 3/20 0.67
HIF1A Q16665 3/20 0.67
CYP3A4 P08684 2/20 0.67
MAPK1 P28482 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
THRB P10828 4/20 0.65
TSHR P16473 8/20 0.50
HPGD P15428 1/20 0.50
HSD17B10 Q99714 1/20 0.45
HCAR2 Q8TDS4 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL238953 0.96 THRB (0.70) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL28543752 0.96 THRB (0.70) ALDH1A1TP53HIF1ACYP3A4MAPK1
Alcohol SCHEMBL7030010 0.92 ALDH1A1 (0.68) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL26062577 0.92 ALDH1A1 (0.62) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL39816 0.90 THRB (0.74) ALDH1A1TP53HIF1ACYP3A4MAPK1
Ethylene Glycol SCHEMBL10426882 0.90 ALDH1A1 (0.66) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL134216 0.90 ALDH1A1 (0.78) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL22264522 0.90 ALDH1A1 (0.78) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL9577936 0.90 ALDH1A1 (0.78) ALDH1A1TP53HIF1ACYP3A4MAPK1
Acrylic Acid SCHEMBL17101615 0.90 THRB (0.64) ALDH1A1TP53HIF1ACYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11576998-B2 High refractive index, high Abbe number intraocular lens materials ALCON INC. (CH) 2023-02-14 US claimed
US-20260147141-A1 SURFACE MODIFIED SILICONE OPHTHALMIC DEVICES BAUSCH + LOMB IRELAND LIMITED (IE) 2026-05-28 US disclosed
US-20260078209-A1 SILICONE HYDROGEL INK BINDER FOR CONTACT LENSES BAUSCH & LOMB IRELAND LTD (IE) 2026-03-19 US disclosed
EP-4683963-A1 SILICONE HYDROGELS Bausch + Lomb Ireland Limited (IE) 2026-01-28 EP disclosed
EP-4683962-A1 MONOFUNCTIONAL SILICONE MONOMERS AND SILICONE HYDROGELS FORMED THEREFROM Bausch + Lomb Ireland Limited (IE) 2026-01-28 EP disclosed
EP-4677398-A1 CONTACT LENS CONTAINING DEPROTECTED ULTRAVIOLET BLOCKERS Bausch + Lomb Ireland Limited (IE) 2026-01-14 EP disclosed
EP-4654920-A1 OPHTHALMIC DEVICES HAVING A HIGH REFRACTIVE INDEX AND ABBE NUMBER Bausch + Lomb Ireland Limited (IE) 2025-12-03 EP disclosed
US-20250334718-A1 SURFACE MODIFIED SILICONE OPHTHALMIC DEVICE BAUSCH & LOMB IRELAND LTD (IE) 2025-10-30 US disclosed
US-20250155808-A1 RESIST COMPOSITION AND METHOD OF FORMING RESIST PATTERN ZEON CORPORATION (JP) 2025-05-15 US disclosed
WO-2025093198-A1 VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC DEVICES BAUSCH + LOMB IRELAND LIMITED (IE) 2025-05-08 WO disclosed
US-20240277895-A1 OPHTHALMIC DEVICES HAVING A HIGH REFRACTIVE INDEX AND ABBE NUMBER JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT 2024-08-22 US disclosed
WO-2024156667-A1 OPHTHALMIC DEVICES HAVING A HIGH REFRACTIVE INDEX AND ABBE NUMBER BAUSCH + LOMB IRELAND LIMITED (IE) 2024-08-02 WO disclosed
WO-2024070672-A1 RESIST COMPOSITION AND METHOD FOR FORMING RESIST PATTERN 日本ゼオン株式会社 2024-04-04 WO disclosed
WO-2023189969-A1 RESIST COMPOSITION AND METHOD FOR FORMING RESIST PATTERN 日本ゼオン株式会社 2023-10-05 WO disclosed
EP-3932906-B1 NOVEL COMPOUND, COMPOSITION CONTAINING SAID COMPOUND, AND CURED OBJECT ADEKA CORP (JP) 2023-07-12 EP disclosed
US-11667609-B2 Compound, composition containing said compound, self-healing material, surface coating agent, paint, adhesive, material for battery and cured product ADEKA CORPORATION (JP) 2023-06-06 US disclosed
US-20230114903-A1 BINDER COMPOSITION FOR SECONDARY BATTERY GRST SINGAPORE PTE. LTD. (SG) 2023-04-13 US disclosed
US-11576998-B2 High refractive index, high Abbe number intraocular lens materials ALCON INC. (CH) 2023-02-14 US disclosed
US-20220153698-A1 NOVEL COMPOUND, COMPOSITION CONTAINING SAID COMPOUND, SELF-HEALING MATERIAL, SURFACE COATING AGENT, PAINT, ADHESIVE, MATERIAL FOR BATTERY AND CURED PRODUCT ADEKA CORPORATION (JP) 2022-05-19 US disclosed
US-7396885-B2 Photo-setting and thermosetting resin composition, process for preparing plugged-through-hole printed wiring board and plugged-through-hole printed wiring board SAN-EI KAGAKU CO., LTD. (JP) 2008-07-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078209-A1 SILICONE HYDROGEL INK BINDER FOR CONTACT LENSES CRYAA, CRYAB, CRYZ ALDH1A1 2751/4885TP53 807/4885HIF1A 889/4885
US-11667609-B2 Compound, composition containing said compound, self-healing material, surface coating agent, paint, adhesive, material for battery and cured product H1-0, H1-10, RAD51 ALDH1A1 323/4885TP53 2667/4885HIF1A 1210/4885
US-20220153698-A1 NOVEL COMPOUND, COMPOSITION CONTAINING SAID COMPOUND, SELF-HEALING MATERIAL, SURFACE COATING AGENT, PAINT, ADHESIVE, MATERIAL FOR BATTERY AND CURED PRODUCT H1-0, H1-10, RAD51 ALDH1A1 367/4885TP53 2848/4885HIF1A 1018/4885
US-20260147141-A1 SURFACE MODIFIED SILICONE OPHTHALMIC DEVICES EPCAM, STIM1, SMCHD1 ALDH1A1 2187/4885TP53 2364/4885HIF1A 989/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.