Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | ATM | Q13315 | 2/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1614490 | 1.00 | LMNA (0.64) | LMNAMAPTNPC1ATMTHRB | |
| Methane SCHEMBL11689712 | 0.98 | LMNA (0.62) | LMNAMAPTNPC1ATMTHRB | |
| SCHEMBL4801322 | 0.95 | LMNA (0.59) | LMNAMAPTNPC1ATMTHRB | |
| SCHEMBL22166847 | 0.91 | MAPT (0.62) | LMNAMAPTNPC1ATMTHRB | |
| SCHEMBL5598686 | 0.87 | LMNA (0.66) | LMNAMAPTNPC1ATMALDH1A1 | |
| SCHEMBL5598683 | 0.87 | LMNA (0.66) | LMNAMAPTNPC1ATMALDH1A1 | |
| SCHEMBL71401 | 0.86 | PTPN1 (0.73) | LMNAMAPTNPC1ATMALDH1A1 | |
| SCHEMBL71402 | 0.86 | PTPN1 (0.73) | LMNAMAPTNPC1ATMALDH1A1 | |
| SCHEMBL5379059 | 0.86 | PTPN1 (0.73) | LMNAMAPTNPC1ATMALDH1A1 | |
| SCHEMBL2627847 | 0.86 | PTPN1 (0.73) | LMNAMAPTNPC1ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020007010-A1 | Process for the preparation of methyl p-vinylbenzoate and p-vinyl benzoic acid, and their use in latex compositions | EASTMAN CHEMICAL COMPANY | 2002-01-17 | — | — | US | claimed |
| US-6313340-B1 | Process for the preparation of methyl p-vinylbenzoate and p-vinyl benzoic acid, and their use in latex compositions | EASTMAN CHEMICAL CORPORATION | 2001-11-06 | — | — | US | claimed |
| EP-1140771-A1 | PROCESS FOR THE PREPARATION OF METHYL P-VINYLBENZOATE AND P-VINYL BENZOIC ACID, AND THEIR USE IN LATEX COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 2001-10-10 | — | — | EP | claimed |
| WO-2000035850-A1 | PROCESS FOR THE PREPARATION OF METHYL P-VINYLBENZOATE AND P-VINYL BENZOIC ACID, AND THEIR USE IN LATEX COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 2000-06-22 | — | — | WO | claimed |
| US-12479797-B2 | Cyclopropyl-amide compounds as dual LSD1/HDAC inhibitors | Jubilant Epicore LLC (US) | 2025-11-25 | — | — | US | disclosed |
| EP-3455204-B1 | CYCLOPROPYL-AMIDE COMPOUNDS AS DUAL LSD1/HDAC INHIBITORS | Jubilant Epicore LLC (US) | 2025-10-29 | — | — | EP | disclosed |
| US-12286426-B2 | Heterocyclic mitochondrial activity inhibitors and uses thereof | Université de Montréal (CA) | 2025-04-29 | — | — | US | disclosed |
| US-12215092-B2 | Pleiotropic pathway modifier compounds and method of treating diseases | PPM BIOPHARMA LLC (US) | 2025-02-04 | — | — | US | disclosed |
| EP-3704111-B1 | HETEROCYCLIC MITOCHONDRIAL ACTIVITY INHIBITORS AND USES THEREOF | UNIV MONTREAL (CA) | 2024-10-09 | — | — | EP | disclosed |
| US-20240300918-A1 | Pleiotropic Pathway Modifier Compounds and Method of Treating Diseases | PPM BIOPHARMA LLC (US) | 2024-09-12 | — | — | US | disclosed |
| WO-2024178348-A2 | PLEIOTROPIC PATHWAY MODIFIER COMPOUNDS AND METHOD OF TREATING DISEASES | PPM BIOPHARMA LLC (US) | 2024-08-29 | — | — | WO | disclosed |
| CN-113166467-B | Polyethylene or polypropylene articles | 巴斯夫欧洲公司 | 2024-03-29 | — | — | CN | disclosed |
| US-5994368-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANALGESICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| CN-1218471-A | Carboline derivatives | ICOS CORP (US) | 1999-06-02 | — | — | CN | disclosed |
| EP-0858452-A1 | THIAZOLE DERIVATIVE AS PROTEIN KINASE C INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-19 | — | — | EP | disclosed |
| WO-1998004536-A1 | THIAZOLE DERIVATIVE AS PROTEIN KINASE C INHIBITORS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1998-02-05 | — | — | WO | disclosed |
| EP-0807105-A1 | PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-19 | — | — | EP | disclosed |
| WO-1996013485-A1 | PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-09 | — | — | WO | disclosed |
| CN-1094035-A | Carboxylic acid derivative contains pharmaceutical composition of these compounds and preparation method thereof | THOMAE GMBH DR K (DE) | 1994-10-26 | — | — | CN | disclosed |
| EP-0604800-A1 | 4- 4- 4-(carboxyalkyl)-phenyl amino carbonyl -phenyl -piperedines as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-07-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12215092-B2 | Pleiotropic pathway modifier compounds and method of treating diseases | SUMO2, SUMO1, SUMO3 | LMNA 4195/4885MAPT 2370/4885NPC1 2910/4885 |
| US-20240300918-A1 | Pleiotropic Pathway Modifier Compounds and Method of Treating Diseases | SUMO2, SUMO1, SUMO3 | LMNA 4195/4885MAPT 2370/4885NPC1 2910/4885 |
| US-12479797-B2 | Cyclopropyl-amide compounds as dual LSD1/HDAC inhibitors | HDAC1, HDAC11, HDAC2 | LMNA 1966/4885MAPT 33/4885NPC1 297/4885 |
| US-12286426-B2 | Heterocyclic mitochondrial activity inhibitors and uses thereof | IDH2, TFAM, IDH1 | LMNA 1657/4885MAPT 4580/4885NPC1 3392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.