SCHEMBL4801322

SCHEMBL4801322

COC(=O)c1ccc(-c2ccc(C=CC(=O)O)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.59
MAPT P10636 3/20 0.59
NPC1 O15118 2/20 0.59
ATM Q13315 2/20 0.57
THRB P10828 1/20 0.57
ALDH1A1 P00352 2/20 0.56
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
PTPN1 P18031 2/20 0.54
MAOB P27338 1/20 0.54
HTT P42858 1/20 0.52
RAB9A P51151 1/20 0.52
HDAC3 O15379 3/20 0.50
HDAC4 P56524 3/20 0.50
HDAC1 Q13547 3/20 0.50
HDAC7 Q8WUI4 3/20 0.50
HDAC2 Q92769 3/20 0.50
HDAC10 Q969S8 3/20 0.50
HDAC11 Q96DB2 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1614490 0.95 LMNA (0.64) LMNAMAPTNPC1ATMTHRB
SCHEMBL1614488 0.95 LMNA (0.64) LMNAMAPTNPC1ATMTHRB
Methane SCHEMBL11689712 0.93 LMNA (0.62) LMNAMAPTNPC1ATMTHRB
SCHEMBL22166847 0.86 MAPT (0.62) LMNAMAPTNPC1ATMTHRB
SCHEMBL7532838 0.85 EGFR (0.60) LMNAMAPTNPC1ALDH1A1MEN1
SCHEMBL7532835 0.85 EGFR (0.60) LMNAMAPTNPC1ALDH1A1MEN1
SCHEMBL5598683 0.82 LMNA (0.66) LMNAMAPTNPC1ATMALDH1A1
SCHEMBL5598686 0.82 LMNA (0.66) LMNAMAPTNPC1ATMALDH1A1
SCHEMBL13899905 0.82 TSHR (0.56) LMNAMAPTNPC1ALDH1A1MEN1
SCHEMBL71401 0.82 PTPN1 (0.73) LMNAMAPTNPC1ATMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7416821-B2 Thermally cured undercoat for lithographic application FUJIFILM ELECTRONIC MATERIALS, U.S.A., INC. (US) 2008-08-26 US disclosed
EP-1743363-A2 THERMALLY CURED UNDERCOAT FOR LITHOGRAPHIC APPLICATION FujiFilm Electronic Materials USA, Inc. (US) 2007-01-17 EP disclosed
US-20050238997-A1 Thermally cured undercoat for lithographic application FUJIFILM ELECTRONIC MATERIALS, U.S.A., INC. 2005-10-27 US disclosed
WO-2005089150-A2 THERMALLY CURED UNDERCOAT FOR LITHOGRAPHIC APPLICATION FUJIFILM ELECTRONIC MATERIALS USA INC. (US) 2005-09-29 WO disclosed