SCHEMBL1614571

SCHEMBL1614571

NC(CC1=CCC(O)(F)C=C1)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 4/20 0.38
PKM P14618 2/20 0.38
PTGS1 P23219 2/20 0.38
ALPI P09923 1/20 0.38
XIAP P98170 1/20 0.38
GRB2 P62993 1/20 0.37
USP2 O75604 3/20 0.35
HSD17B10 Q99714 3/20 0.35
ALOX15 P16050 2/20 0.35
HIF1A Q16665 2/20 0.35
KDM4E B2RXH2 2/20 0.35
RECQL P46063 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
CYP3A4 P08684 2/20 0.35
RGS12 O14924 1/20 0.35
CYP2C9 P11712 1/20 0.35
NFKB1 P19838 1/20 0.35
CASP1 P29466 1/20 0.35
BRCA1 P38398 1/20 0.35
THPO P40225 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3284389 1.00 SLC7A5 (0.38) SLC7A5PKMPTGS1ALPIXIAP
SCHEMBL8740472 0.86 SLC7A5 (0.39) SLC7A5PKMPTGS1ALPIXIAP
SCHEMBL4262731 0.84 SLC7A5 (0.40) SLC7A5PKMPTGS1ALPIXIAP
SCHEMBL2901551 0.84 SLC7A5 (0.37) SLC7A5PKMPTGS1ALPIXIAP
SCHEMBL7200971 0.83 SLC7A5 (0.39) SLC7A5PKMPTGS1ALPIXIAP
SCHEMBL2389248 0.82 SLC7A5 (0.38) SLC7A5PKMPTGS1ALPIXIAP
SCHEMBL29436333 0.82 SLC7A5 (0.38) SLC7A5PKMPTGS1ALPIXIAP
SCHEMBL28669915 0.82 SLC7A5 (0.38) SLC7A5PKMPTGS1ALPIXIAP
SCHEMBL28679240 0.82 SLC7A5 (0.39) SLC7A5PKMPTGS1ALPIXIAP
SCHEMBL229096 0.82 SLC7A5 (0.38) SLC7A5PKMPTGS1ALPIXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0954596-B1 ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF TAXUS SPECIES PHYTON INC (US) 2006-01-04 EP claimed
EP-1538214-A1 Enhanced production of taxanes by cell cultures of taxus species PHYTON, INC. (US) 2005-06-08 EP claimed
EP-0954596-A1 ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF $i(TAXUS) SPECIES PHYTON, INC. (US) 1999-11-10 EP claimed
WO-1997044476-A1 ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF TAXUS SPECIES PHYTON, INC. (US) 1997-11-27 WO claimed
US-20130017582-A1 ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES PHYTON HOLDINGS, LLC (US) 2013-01-17 US disclosed
US-8338143-B2 Enhanced production of paclitaxel and taxanes by cell cultures of Taxus species PHYTON HOLDINGS, LLC (US) 2012-12-25 US disclosed
US-20110086397-A1 ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES PHYTON HOLDINGS, LLC (US) 2011-04-14 US disclosed
US-20080108115-A1 ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES DFB BIOTECH, INCORPORATED (US) 2008-05-08 US disclosed
US-7264951-B1 Enhanced production of taxol and taxanes by cell cultures of Taxus species PHYTON, INC. (US) 2007-09-04 US disclosed
EP-0954596-B1 ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF TAXUS SPECIES PHYTON INC (US) 2006-01-04 EP disclosed
EP-1538214-A1 Enhanced production of taxanes by cell cultures of taxus species PHYTON, INC. (US) 2005-06-08 EP disclosed
EP-1398384-A1 Enhanced production of taxanes by cell cultures of taxus species Phyton Inc. (US) 2004-03-17 EP disclosed
EP-0954596-A1 ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF $i(TAXUS) SPECIES PHYTON, INC. (US) 1999-11-10 EP disclosed
WO-1997044476-A1 ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF TAXUS SPECIES PHYTON, INC. (US) 1997-11-27 WO disclosed