Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.35 |
| ▸ | USP2 | O75604 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4262731 | 0.84 | SLC7A5 (0.40) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL29054244 | 0.84 | SLC7A5 (0.37) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL7200971 | 0.83 | SLC7A5 (0.39) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL3284389 | 0.82 | SLC7A5 (0.38) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL28669915 | 0.82 | SLC7A5 (0.38) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL2389248 | 0.82 | SLC7A5 (0.38) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL29436333 | 0.82 | SLC7A5 (0.38) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL28679240 | 0.82 | SLC7A5 (0.39) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL1614571 | 0.82 | SLC7A5 (0.38) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL29964933 | 0.81 | SLC7A5 (0.37) | SLC7A5PKMPTGS1ALPIXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024086738-A2 | COMPOSITIONS AND METHODS OF USE FOR INTEINS | GRO BIOSCIENCES INC. (US) | 2024-04-25 | — | — | WO | claimed |
| WO-2024086738-A2 | COMPOSITIONS AND METHODS OF USE FOR INTEINS | GRO BIOSCIENCES INC. (US) | 2024-04-25 | — | — | WO | disclosed |
| CN-117534595-A | Isotopically enriched 3-amino-1-propanesulfonic acid derivatives and uses thereof | 润佳（苏州）医药科技有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-116785269-A | Homotaurine derivatives and uses thereof | 润佳（苏州）医药科技有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-116763768-A | Isotopically enriched 3-amino-1-propanesulfonic acid derivatives and uses thereof | 润佳（苏州）医药科技有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-113660957-A | Compositions, methods, and uses comprising antibody-TLR agonist conjugates | AMBRX公司 | 2021-11-16 | — | — | CN | disclosed |
| EP-2793027-B1 | Unnatural reactive amino acid genetic code additions | SCRIPPS RESEARCH INST (US) | 2019-11-13 | — | — | EP | disclosed |
| US-9797908-B2 | Unnatural reactive amino acid genetic code additions | THE SCRIPPS RESEARCH INSTITUTE (US) | 2017-10-24 | — | — | US | disclosed |
| US-9580721-B2 | Expanding the eukaryotic genetic code | The Scripps Reserach Institute (US) | 2017-02-28 | — | — | US | disclosed |
| EP-2410331-B1 | Aminoacyl-tRNA synthetase for aminoacylation tRNA with unnatural amino acids | SCRIPPS RESEARCH INST (US) | 2015-09-23 | — | — | EP | disclosed |
| US-20080176277-A1 | Expanding the eukaryotic genetic code | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-07-24 | — | — | US | disclosed |
| US-20070166791-A1 | Expanding the eukaryotic genetic code | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-07-19 | — | — | US | disclosed |
| US-20070154952-A1 | Expanding the eukaryotic genetic code | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-07-05 | — | — | US | disclosed |
| US-20060246509-A1 | protein containing an amino acid that carries an azido or alkynyl group for conjugation to a second molecule such as polymer, label or drug by a [3+2] cycloaddition; translation biochemistry in eukaryotic cells; gene expression inhibitors | THE SCRIPPS RESEARCH INSTITUTE | 2006-11-02 | — | — | US | disclosed |
| US-20050130949-A1 | Cyclic polyamine compounds for cancer therapy | SLIL BIOMEDICAL CORPORATION | 2005-06-16 | — | — | US | disclosed |
| US-20050009049-A1 | Expanding the eukaryotic genetic code | THE SCRIPPS RESEARCH INSTITUTE (US) | 2005-01-13 | — | — | US | disclosed |
| US-20040265952-A1 | protein containing a modified amino acid that carries an azido or alkynyl group for conjugation to a second molecule such as polymer, label or drug that carries an alkynyl or azido group; translation biochemistry in eukaryotic cells; gene expression inhibitors | THE SCRIPPS RESEARCH INSTITUTE (US) | 2004-12-30 | — | — | US | disclosed |
| EP-1305299-A1 | CYCLIC POLYAMINE COMPOUNDS FOR CANCER THERAPY | SLIL Biomedical Corporation (US) | 2003-05-02 | — | — | EP | disclosed |
| US-20030072715-A1 | Cyclic polyamine compounds for cancer therapy | UNIVERSITY OF ZURICH (SE) | 2003-04-17 | — | — | US | disclosed |
| WO-2002010142-A1 | CYCLIC POLYAMINE COMPOUNDS FOR CANCER THERAPY | SLIL BIOMEDICAL CORPORATION (US) | 2002-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030072715-A1 | Cyclic polyamine compounds for cancer therapy | SRM, SMS, CATSPER1 | SLC7A5 713/4885PKM 161/4885PTGS1 1053/4885 |
| US-20050130949-A1 | Cyclic polyamine compounds for cancer therapy | SRM, ADORA3, ADORA1 | SLC7A5 696/4885PKM 303/4885PTGS1 869/4885 |
| US-20070154952-A1 | Expanding the eukaryotic genetic code | NSUN3, AARS1, TRMT1 | SLC7A5 263/4885PKM 3536/4885PTGS1 3470/4885 |
| US-20050009049-A1 | Expanding the eukaryotic genetic code | NSUN3, AARS1, TRMT1 | SLC7A5 263/4885PKM 3536/4885PTGS1 3470/4885 |
| US-20060246509-A1 | protein containing an amino acid that carries an azido or alkynyl group for conjugation to a second molecule such as polymer, label or drug by a [3+2] cycloaddition; translation biochemistry in eukaryotic cells; gene expression inhibitors | AARS1, ASNS, KARS1 | SLC7A5 431/4885PKM 3070/4885PTGS1 4151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.