Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | GRB2 | P62993 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | RGS12 | O14924 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1614571 | 1.00 | SLC7A5 (0.38) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL8740472 | 0.86 | SLC7A5 (0.39) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL4262731 | 0.84 | SLC7A5 (0.40) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL2901551 | 0.84 | SLC7A5 (0.37) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL7200971 | 0.83 | SLC7A5 (0.39) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL2389248 | 0.82 | SLC7A5 (0.38) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL29436333 | 0.82 | SLC7A5 (0.38) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL28669915 | 0.82 | SLC7A5 (0.38) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL28679240 | 0.82 | SLC7A5 (0.39) | SLC7A5PKMPTGS1ALPIXIAP | |
| SCHEMBL229096 | 0.82 | SLC7A5 (0.38) | SLC7A5PKMPTGS1ALPIXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112442011-B | Prodrug compound and application thereof in treating cancers | 润佳（苏州）医药科技有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-112442009-B | Deuterated compounds and their use for treating cancer | 润佳（苏州）医药科技有限公司 | 2023-10-03 | — | — | CN | disclosed |
| US-11685938-B2 | Muconic acid production from genetically engineered microorganisms | PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) | 2023-06-27 | — | — | US | disclosed |
| EP-3423563-B1 | IMPROVED MUCONIC ACID PRODUCTION FROM GENETICALLY ENGINEERED MICROORGANISMS | PTT GLOBAL CHEMICAL PUBLIC CO LTD (TH) | 2023-05-24 | — | — | EP | disclosed |
| CN-109415684-B | Improved muconic acid production from genetically engineered microorganisms | PTT全球化学公众有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-114174316-A | Modified peptides and related methods of use | 新颖疗法的先进技术有限责任公司 | 2022-03-11 | — | — | CN | disclosed |
| US-20210277429-A1 | MUCONIC ACID PRODUCTION FROM GENETICALLY ENGINEERED MICROORGANISMS | PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) | 2021-09-09 | — | — | US | disclosed |
| US-20200181658-A1 | IMPROVED MUCONIC ACID PRODUCTION FROM GENETICALLY ENGINEERED MICROORGANISMS | PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) | 2020-06-11 | — | — | US | disclosed |
| EP-3312267-B1 | PRODUCTION OF MUCONIC ACID FROM GENETICALLY ENGINEERED MICROORGANISMS | PTT GLOBAL CHEMICAL PUBLIC CO LTD (TH) | 2020-03-11 | — | — | EP | disclosed |
| US-20190345437-A1 | PRODUCTION OF MUCONIC ACID FROM GENETICALLY ENGINEERED MICROORGANISMS | PTTGC INNOVATION AMERICA CORPORATION (US) | 2019-11-14 | — | — | US | disclosed |
| EP-2809771-B1 | PRODUCTION OF MUCONIC ACID FROM GENETICALLY ENGINEERED MICROORGANISMS | MYRIANT CORP (US) | 2017-12-27 | — | — | EP | disclosed |
| US-20150044755-A1 | PRODUCTION OF MUCONIC ACID FROM GENETICALLY ENGINEERED MICROORGANISMS | MYRIANT CORPORATION (US) | 2015-02-12 | — | — | US | disclosed |
| EP-2809771-A1 | PRODUCTION OF MUCONIC ACID FROM GENETICALLY ENGINEERED MICROORGANISMS | Myriant Corporation (US) | 2014-12-10 | — | — | EP | disclosed |
| WO-2013116244-A1 | PRODUCTION OF MUCONIC ACID FROM GENETICALLY ENGINEERED MICROORGANISMS | MYRIANT CORPORATION (US) | 2013-08-08 | — | — | WO | disclosed |
| EP-1616940-B1 | L-tyrosine-producing bacterium and a method for producing L-tyrosine | AJINOMOTO KK (JP) | 2013-08-07 | — | — | EP | disclosed |
| US-7709242-B2 | L-tyrosine producing bacterium and a method for producing L-tyrosine | AJINOMOTO CO., INC. (JP) | 2010-05-04 | — | — | US | disclosed |
| US-20090104683-A1 | L-TYROSINE-PRODUCING BACTERIUM AND A METHOD FOR PRODUCING L-TYROSINE | TAKAI ATSUKO | 2009-04-23 | — | — | US | disclosed |
| US-7482140-B2 | L-tyrosine-producing bacterium and a method for producing L-tyrosine | AJINOMOTO CO., INC. (JP) | 2009-01-27 | — | — | US | disclosed |
| EP-1616940-A1 | L-tyrosine-producing bacterium and a method for producing L-tyrosine | Ajinomoto Co., Inc. (JP) | 2006-01-18 | — | — | EP | disclosed |
| US-20050277179-A1 | L-tyrosine-producing bacterium and a method for producing L-tyrosine | AJINOMOTO CO., INC. (JP) | 2005-12-15 | — | — | US | disclosed |