Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5159 | 1.00 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL7283678 | 1.00 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL1477516 | 1.00 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL1476914 | 1.00 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL14720581 | 0.95 | — | — | |
| SCHEMBL10873496 | 0.85 | — | — | |
| SCHEMBL7815 | 0.77 | — | — | |
| SCHEMBL14740988 | 0.77 | — | — | |
| SCHEMBL9938216 | 0.73 | PNMT (0.34) | — | |
| SCHEMBL37649 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107072946-B | Lipids and lipid compositions for delivery of active agents | 诺华股份有限公司 | 2022-01-11 | — | — | CN | disclosed |
| CN-107879960-B | Lipids and lipid compositions for delivery of active ingredients | 诺华股份有限公司 | 2021-06-22 | — | — | CN | disclosed |
| CN-106794141-B | Method for encapsulating nucleic acids in lipid nanoparticle hosts | 诺华股份有限公司 | 2021-05-28 | — | — | CN | disclosed |
| US-11013696-B2 | Lipids and lipid compositions for the delivery of active agents | NOVARTIS AG (CH) | 2021-05-25 | — | — | US | disclosed |
| US-10792361-B2 | Lipids and lipid compositions for the delivery of active agents | NOVARTIS AG (CH) | 2020-10-06 | — | — | US | disclosed |
| US-20190321295-A1 | Method of Encapsulating a Nucleic Acid in a Lipid Nanoparticle Host | NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. | 2019-10-24 | — | — | US | disclosed |
| US-20180369386-A1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH INC. | 2018-12-27 | — | — | US | disclosed |
| US-9504747-B2 | Lipids and lipid compositions for the delivery of active agents | NOVARTIS AG (CH) | 2016-11-29 | — | — | US | disclosed |
| US-20140303232-A1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | NOVARTIS AG (CH) | 2014-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190321295-A1 | Method of Encapsulating a Nucleic Acid in a Lipid Nanoparticle Host | POLN, POLRMT, RNGTT | ALDH1A1 2314/4885 |
| US-20180369386-A1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | LIPA, LPAR1, LPAR4 | ALDH1A1 2488/4885 |
| US-11013696-B2 | Lipids and lipid compositions for the delivery of active agents | PHOSPHO1, SGMS1, LIPA | ALDH1A1 1564/4885 |
| US-10792361-B2 | Lipids and lipid compositions for the delivery of active agents | LIPA, LPAR1, LPAR4 | ALDH1A1 2488/4885 |
| US-20140303232-A1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | LIPA, LPAR1, LPAR4 | ALDH1A1 2488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.