Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395344 | 0.83 | EPHX1 (0.53) | EPHX1TDP1CA12CA1CA2 | |
| SCHEMBL8396779 | 0.81 | EPHX1 (0.57) | EPHX1TDP1CA12CA1CA2 | |
| SCHEMBL8392780 | 0.81 | EPHX1 (0.57) | EPHX1TDP1CA12CA1CA2 | |
| SCHEMBL6614441 | 0.80 | EPHX1 (0.54) | EPHX1TDP1TSHRKMT2A | |
| Hydrochloric Acid SCHEMBL3668305 | 0.79 | EPHX1 (0.55) | EPHX1TDP1CA12CA1CA2 | |
| SCHEMBL8393651 | 0.78 | EPHX1 (0.48) | EPHX1TDP1CA12CA1CA2 | |
| SCHEMBL7904682 | 0.77 | TDP1 (0.54) | EPHX1SMN1; SMN2TDP1CA12CA1 | |
| SCHEMBL8290413 | 0.77 | — | — | |
| SCHEMBL7909626 | 0.77 | PKM (0.36) | EPHX1HTR2CMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL16145882 | 0.76 | ACHE (0.50) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8927763-B2 | Method for preparing aliphatic diisocyanate | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2015-01-06 | — | — | US | claimed |
| US-20140303399-A1 | METHOD FOR PREPARING ALIPHATIC DIISOCYANATE | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2014-10-09 | — | — | US | claimed |
| US-8927763-B2 | Method for preparing aliphatic diisocyanate | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2015-01-06 | — | — | US | disclosed |
| US-20140303399-A1 | METHOD FOR PREPARING ALIPHATIC DIISOCYANATE | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2014-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140303399-A1 | METHOD FOR PREPARING ALIPHATIC DIISOCYANATE | ALKBH3, DDC, ALKBH5 | EPHX1 3411/4885EPHX2 1207/4885NPSR1 4035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.