SCHEMBL16147382

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1618019	0.90	ALDH1A1 (0.58)	ALOX15ALDH1A1HPGDHSD17B10TDP1
	SCHEMBL9973589	0.90	ALDH1A1 (0.58)	ALOX15ALDH1A1HPGDHSD17B10TDP1
	SCHEMBL13368742	0.89	ESR1 (0.62)	ALOX15ALDH1A1HPGDHSD17B10TDP1
	SCHEMBL12387991	0.87	ALDH1A1 (0.52)	ALOX15ALDH1A1HPGDHSD17B10TDP1
	Toluene SCHEMBL28953594	0.83	ALDH1A1 (0.73)	ALOX15ALDH1A1HPGDHSD17B10TDP1
	SCHEMBL2781063	0.82	ESR1 (0.69)	ALOX15ALDH1A1HPGDHSD17B10TDP1
	SCHEMBL4626064	0.82	ESR1 (0.69)	ALOX15ALDH1A1HPGDHSD17B10TDP1
	SCHEMBL8671538	0.82	TSHR (0.57)	ALDH1A1HPGDTDP1ESR1ESR2
	SCHEMBL11475507	0.82	CSNK2A1 (0.59)	ALDH1A1HPGDESR1ESR2ALOX5
	SCHEMBL9632111	0.82	TSHR (0.57)	ALDH1A1HPGDTDP1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.