SCHEMBL4626064

SCHEMBL4626064

Cc1cc(C(c2ccccc2)(c2ccccc2)c2ccccc2)ccc1O

nearest known ligand 0.69

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 15/20 0.69
ESR2 Q92731 9/20 0.69
AR P10275 3/20 0.53
TDP1 Q9NUW8 2/20 0.46
TP53 P04637 1/20 0.46
ALDH1A1 P00352 2/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
HSD17B10 Q99714 1/20 0.43
PDE10A Q9Y233 1/20 0.43
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.41
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
HSP90AA1 P07900 1/20 0.41
RAB9A P51151 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2781063 1.00 ESR1 (0.69) ESR1ESR2ARTDP1TP53
SCHEMBL13368742 0.94 ESR1 (0.62) ESR1ESR2ARTDP1TP53
SCHEMBL22035220 0.89 ESR1 (0.57) ESR1ESR2ARTDP1TP53
SCHEMBL673977 0.89 ESR1 (0.70) ESR1ESR2ARTDP1TP53
SCHEMBL12387991 0.85 ALDH1A1 (0.52) ESR1ESR2ARTDP1ALDH1A1
SCHEMBL2864420 0.84 ESR1 (0.55) ESR1ESR2ARTDP1TP53
SCHEMBL1618019 0.83 ALDH1A1 (0.58) ESR1ESR2TDP1ALDH1A1HPGD
SCHEMBL9973589 0.83 ALDH1A1 (0.58) ESR1ESR2TDP1ALDH1A1HPGD
SCHEMBL16147382 0.82 ALOX15 (0.53) ESR1ESR2TDP1ALDH1A1HPGD
SCHEMBL835556 0.82 ESR1 (1.00) ESR1ESR2ARTDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1401851-B8 TWO-STAGE PROTECTIVE GROUPS FOR THE SYNTHESIS OF BIOPOLYMERS FEBIT HOLDING GMBH (DE) 2008-09-10 EP disclosed
EP-1401851-B1 TWO-STAGE PROTECTIVE GROUPS FOR THE SYNTHESIS OF BIOPOLYMERS FEBIT BIOTECH GMBH (DE) 2008-07-02 EP disclosed
US-7355036-B2 Two-stage protective groups for the synthesis of biopolymers FEBIT AG (DE) 2008-04-08 US disclosed
US-20040197851-A1 Two-stage protective groups for the synthesis of biopolymers MR. CHRISTOPHER SEAGON, ESQ. (DE) 2004-10-07 US disclosed
EP-1401851-A1 TWO-STAGE PROTECTIVE GROUPS FOR THE SYNTHESIS OF BIOPOLYMERS Febit AG (DE) 2004-03-31 EP disclosed
WO-2003004510-A1 TWO-STAGE PROTECTIVE GROUPS FOR THE SYNTHESIS OF BIOPOLYMERS FEBIT AG (DE) 2003-01-16 WO disclosed
US-4219219-A Developers for pressure-sensitive recording and developing sheets containing them FUJI PHOTO FILM CO., LTD. (JP) 1980-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040197851-A1 Two-stage protective groups for the synthesis of biopolymers CTRB2, OGG1, CPB2 ESR1 4453/4885ESR2 2975/4885AR 4641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.