SCHEMBL1618019

SCHEMBL1618019

Oc1ccc(C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.58
ALOX15 P16050 3/20 0.58
HPGD P15428 2/20 0.58
HSD17B10 Q99714 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
ESR1 P03372 7/20 0.47
ESR2 Q92731 3/20 0.47
ALOX5 P09917 1/20 0.46
IDH1 O75874 1/20 0.42
APP P05067 3/20 0.41
CYP3A4 P08684 2/20 0.40
SIRT1 Q96EB6 1/20 0.40
CYP2D6 P10635 1/20 0.40
IGF1R P08069 1/20 0.39
MAPT P10636 2/20 0.39
RECQL P46063 2/20 0.39
KDM4E B2RXH2 1/20 0.39
NPC1 O15118 1/20 0.39
CA12 O43570 1/20 0.39
GMNN O75496 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9973589 1.00 ALDH1A1 (0.58) ALDH1A1ALOX15HPGDHSD17B10TDP1
SCHEMBL13368742 0.90 ESR1 (0.62) ALDH1A1ALOX15HPGDHSD17B10TDP1
SCHEMBL16147382 0.90 ALOX15 (0.53) ALDH1A1ALOX15HPGDHSD17B10TDP1
SCHEMBL12387991 0.89 ALDH1A1 (0.52) ALDH1A1ALOX15HPGDHSD17B10TDP1
SCHEMBL7194660 0.88 ALDH1A1 (0.71) ALDH1A1ALOX15HPGDHSD17B10TDP1
SCHEMBL28558344 0.83 ESR1 (0.44) ALDH1A1ALOX15HPGDHSD17B10TDP1
SCHEMBL2781063 0.83 ESR1 (0.69) ALDH1A1ALOX15HPGDHSD17B10TDP1
SCHEMBL4626064 0.83 ESR1 (0.69) ALDH1A1ALOX15HPGDHSD17B10TDP1
SCHEMBL11590575 0.81 ESR2 (0.52) ALDH1A1ALOX15HPGDHSD17B10TDP1
SCHEMBL833875 0.81 ESR1 (0.43) ALDH1A1ALOX15HPGDHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4665410-A THERMOGRAPHY RICOH COMPANY, LTD. (JP) 1987-05-12 US claimed
EP-3305539-B1 THERMOSENSITIVE RECORDING MATERIAL AND METHOD FOR PRODUCING SAME FUJIFILM CORP (JP) 2021-04-14 EP disclosed
CN-107531069-B Thermosensitive recording material and method for producing same 富士胶片株式会社 2020-07-10 CN disclosed
US-10272708-B2 Thermosensitive recording material and method for manufacturing the same FUJIFILM CORPORATION (JP) 2019-04-30 US disclosed
US-10259763-B2 Tritylated ethers DOW GLOBAL TECHNOLOGIES LLC (US) 2019-04-16 US disclosed
EP-3305539-A1 THERMOSENSITIVE RECORDING MATERIAL AND METHOD FOR PRODUCING SAME FUJIFILM Corporation (JP) 2018-04-11 EP disclosed
US-20180043717-A1 THERMOSENSITIVE RECORDING MATERIAL AND METHOD FOR MANUFACTURING THE SAME FUJIFILM CORPORATION (JP) 2018-02-15 US disclosed
EP-2995606-B1 TRITYLATED ETHERS DOW GLOBAL TECHNOLOGIES LLC (US) 2017-03-29 EP disclosed
EP-2707467-B1 TRITYLATED ETHERS AND METHOD FOR MARKING LIQUID FUELS DOW GLOBAL TECHNOLOGIES LLC (US) 2017-03-15 EP disclosed
EP-2844630-B1 TRITYLATED ETHERS DOW GLOBAL TECHNOLOGIES LLC (US) 2016-09-07 EP disclosed
EP-0400671-A2 Heat-sensitive stencil sheet TOMOEGAWA PAPER CO. LTD. (JP) 1990-12-05 EP disclosed
EP-0114111-B1 HEAT-SENSITIVE IMAGING SHEET MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-03-01 EP disclosed
US-4665410-A THERMOGRAPHY RICOH COMPANY, LTD. (JP) 1987-05-12 US disclosed
US-4631084-A FERRIC STEARATE-PHENOL COMPLEX AND NON-COMPLEXING PHENOL COLOR INTENSIFIER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-12-23 US disclosed
US-4613878-A DECOLORIZING AGENT COMPRISING AROMATIC DIAMIDE OR PIPERAZINE DERIVATIVE, HAVING TWO ACYLAMINO GROUPS RICOH COMPANY, LTD. (JP) 1986-09-23 US disclosed
US-4531141-A Heat-sensitive composition and imaging sheet incorporating same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-07-23 US disclosed
EP-0114111-A2 Heat-sensitive imaging sheet MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-07-25 EP disclosed
EP-0012587-B1 THERMO-SENSITIVE MULTI-COLOR RECORDING MATERIAL AND PROCESS FOR PREPARATION THEREOF Ricoh Company, Ltd (JP) 1983-05-25 EP disclosed
US-4311750-A DISCOLORING LAYER OF CROSSLINKING RESIN DISPOSED BETWEEN COLORING LAYERS RICOH COMPANY LIMITED (JP) 1982-01-19 US disclosed
EP-0012587-A1 Thermo-sensitive multi-color recording material and process for preparation thereof Ricoh Company, Ltd (JP) 1980-06-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10259763-B2 Tritylated ethers HTR3C, AR, HTR2C ALDH1A1 2040/4885ALOX15 1623/4885HPGD 3866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.