Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 3/20 | 0.37 |
| ▸ | CES1 | P23141 | 3/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4067213 | 0.94 | CYP3A4 (0.50) | TDP1CYP3A4ESR1ESR2CES2 | |
| SCHEMBL10810735 | 0.92 | CYP3A4 (0.48) | TDP1CYP3A4ESR1ESR2CES2 | |
| SCHEMBL10370405 | 0.92 | CYP3A4 (0.48) | TDP1CYP3A4ESR1ESR2CES2 | |
| SCHEMBL27869350 | 0.92 | CYP3A4 (0.48) | TDP1CYP3A4ESR1ESR2CES2 | |
| SCHEMBL2648008 | 0.92 | CYP3A4 (0.48) | TDP1CYP3A4ESR1ESR2CES2 | |
| SCHEMBL5565882 | 0.92 | CYP3A4 (0.48) | TDP1CYP3A4ESR1ESR2CES2 | |
| SCHEMBL8165832 | 0.92 | CYP3A4 (0.48) | TDP1CYP3A4ESR1ESR2CES2 | |
| SCHEMBL7857041 | 0.92 | CYP3A4 (0.48) | TDP1CYP3A4ESR1ESR2CES2 | |
| SCHEMBL9169189 | 0.92 | CYP3A4 (0.48) | TDP1CYP3A4ESR1ESR2CES2 | |
| SCHEMBL455480 | 0.92 | CYP3A4 (0.48) | TDP1CYP3A4ESR1ESR2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105694857-B | A kind of Mitochondrially targeted nitrosyl hydrogen molecule fluorescence probe and its preparation method and application | 济南大学 | 2018-02-13 | — | — | CN | claimed |
| CN-105694857-A | Nitrosyl hydrogen molecular fluorescent probe for mitochondria targeting and preparation method and application thereof | 济南大学 | 2016-06-22 | — | — | CN | claimed |
| US-20260078082-A1 | COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | MODERNATX INC (US) | 2026-03-19 | — | — | US | disclosed |
| US-20260069549-A1 | COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | MODERNATX INC (US) | 2026-03-12 | — | — | US | disclosed |
| EP-4186888-B1 | COMPOUND AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | MODERNATX INC (US) | 2025-11-26 | — | — | EP | disclosed |
| US-12410347-B2 | Adhesive composition, and coverlay film and printed circuit board that include the same | DOOSAN CORPORATION (KR) | 2025-09-09 | — | — | US | disclosed |
| US-12404232-B2 | Compounds and compositions for intracellular delivery of therapeutic agents | MODERNATX, INC. (US) | 2025-09-02 | — | — | US | disclosed |
| US-20250228777-A1 | COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | ARES CAPITAL CORPORATION, AS AGENT | 2025-07-17 | — | — | US | disclosed |
| US-12324859-B2 | Compounds and compositions for intracellular delivery of therapeutic agents | MODERNATX, INC. (US) | 2025-06-10 | — | — | US | disclosed |
| US-12263248-B2 | Compounds and compositions for intracellular delivery of therapeutic agents | MODERNATX, INC. (US) | 2025-04-01 | — | — | US | disclosed |
| CN-119684252-A | Synthesis method of carbon dioxide-based cyclic carbonate | 福建久策气体股份有限公司 | 2025-03-25 | — | — | CN | disclosed |
| EP-0005858-B1 | PREPARATION OF POLYARYLATES | UNION CARBIDE CORPORATION (US) | 1983-05-11 | — | — | EP | disclosed |
| EP-0069810-A1 | Novel dibenzoxepins, their preparation, compositions containing them and the use of dibenzoxepins in the treatment of allergic conditions | MERCK & CO. INC. (US) | 1983-01-19 | — | — | EP | disclosed |
| US-4302574-A | Phosphonium phenoxide catalysts for promoting reacting of epoxides with phenols and/or carboxylic acids | THE DOW CHEMICAL COMPANY (US) | 1981-11-24 | — | — | US | disclosed |
| US-4282365-A | Dibenz[b,e]oxepin compounds | MERCK & CO., INC. (US) | 1981-08-04 | — | — | US | disclosed |
| EP-0019852-A1 | Phosphonium phenoxide catalysts, epoxy resin containing same and process for promoting reaction of epoxides with phenols and/or carboxylic acids | THE DOW CHEMICAL COMPANY (US) | 1980-12-10 | — | — | EP | disclosed |
| US-4229565-A | BY FORMATION OF THE ACYL CHLORIDE THEN POLYMERIZING TO FORM HIGH MOLECULAR WEIGHT, HEAT RESISTANT POLYESTERS | UNION CARBIDE CORPORATION (US) | 1980-10-21 | — | — | US | disclosed |
| US-4228180-A | 7-Oxabicycloheptane and 7-oxabicycloheptene prostaglandin analogs | E. R. SQUIBB & SONS, INC. (US) | 1980-10-14 | — | — | US | disclosed |
| EP-0005858-A1 | Preparation of polyarylates | UNION CARBIDE CORPORATION (US) | 1979-12-12 | — | — | EP | disclosed |
| US-4073933-A | ANTIULCER, ANTISECRETORY, CNS REGULATORS, AND LABOR INDUCERS | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12324859-B2 | Compounds and compositions for intracellular delivery of therapeutic agents | LNPK, PLTP, PLIN3 | TDP1 3724/4885CYP3A4 4876/4885ESR1 4106/4885 |
| US-12263248-B2 | Compounds and compositions for intracellular delivery of therapeutic agents | LNPK, PLTP, PLIN3 | TDP1 3724/4885CYP3A4 4876/4885ESR1 4106/4885 |
| US-20260078082-A1 | COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | PHOSPHO1, LIPC, SDCBP | TDP1 2108/4885CYP3A4 4751/4885ESR1 4590/4885 |
| US-20260069549-A1 | COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | SIN3A, PLIN3, MSR1 | TDP1 4468/4885CYP3A4 4751/4885ESR1 3709/4885 |
| US-12404232-B2 | Compounds and compositions for intracellular delivery of therapeutic agents | LNPK, PLTP, PLIN3 | TDP1 3724/4885CYP3A4 4876/4885ESR1 4106/4885 |
| US-20250228777-A1 | COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | LNPK, PLTP, PLIN3 | TDP1 3724/4885CYP3A4 4876/4885ESR1 4106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.