Sorbitol

Sorbitol

SCHEMBL1614938

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO.[KH]

nearest known ligand 0.92

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.92
L3MBTL1 Q9Y468 1/20 0.92
TDP1 Q9NUW8 2/20 0.85
KDM4E B2RXH2 2/20 0.55
PDE4A P27815 1/20 0.55
USP2 O75604 1/20 0.50
SLCO1B1 Q9Y6L6 1/20 0.50
ALDH1A1 P00352 2/20 0.41
MAPT P10636 1/20 0.38
TOP1 P11387 1/20 0.37
MGAM O43451 2/20 0.34
SI P14410 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mannitol SCHEMBL9755015 1.00 LMNA (0.92) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL13187369 0.96 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL2477078 0.96 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL2297640 0.96 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL20594082 0.96 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL23066399 0.96 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Sorbitol SCHEMBL763 0.96 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL21837180 0.96 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL20594083 0.96 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL20567656 0.96 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210038500-A1 DICLOFENAC AND HYALURONIC ACID COMBINATION TREATMENT FOR ORAL LEUKPOPLAKIA EHRENPREIS ELI D (US) 2021-02-11 US claimed
WO-2020160344-A1 DICLOFENAC AND HYALURONIC ACID COMBINATION TREATMENT FOR ORAL LEUKPOPLAKIA EHRENPREIS ELI D (US) 2020-08-06 WO claimed
US-20200179268-A1 DICLOFENAC AND HYALURONIC ACID COMBINATION TREATMENT FOR ORAL LEUKPOPLAKIA GI PHARMACEUTICALS, INC. AKS E2BIO CONSULTANTS 2020-06-11 US claimed
CN-102320869-B Potassium sorbitol liquid fertilizer JIANGMEN YINGHAO AGRICULTURAL TECHNOLOGY CO., LTD. (CN) 2014-10-29 CN claimed
EP-2489638-B1 APPARATUS FOR REDUCING WASTE LITHOGRAPHIC PRINTING PLATE DEVELOPING LIQUID FUJIFILM GLOBAL GRAPHIC SYSTEMS CO LTD (JP) 2014-07-23 EP claimed
EP-2489638-A1 APPARATUS FOR REDUCING WASTE LITHOGRAPHIC PRINTING PLATE DEVELOPING LIQUID Fujifilm Graphic Systems Co., Ltd. (JP) 2012-08-22 EP claimed
US-7319032-B2 Non-sugar sweeteners for use in test devices MEDTOX (US) 2008-01-15 US claimed
US-7285426-B2 Bulking materials containing starch reagent for use in test devices MEDTOX SCIENTIFIC, INC. (US) 2007-10-23 US claimed
WO-2006036212-A2 NON-SUGAR SWEETENERS FOR USE IN TEST DEVICES MEDTOX SCIENTIFIC, INC. (US) 2006-04-06 WO claimed
US-20050255608-A1 Bulking materials containing starch reagent for use in test devices MEDTOX SCIENTIFIC, INC. (US) 2005-11-17 US claimed
US-20050239214-A1 Non-sugar sweeteners for use in test devices MEDTOX SCIENTIFIC, INC. (US) 2005-10-27 US claimed
WO-1999005987-A1 TOOTH WHITENING SYSTEM ANDERSON MICHAEL R (US) 1999-02-11 WO claimed
EP-3266457-B1 BILE ACID RECYCLING INHIBITORS FOR TREATMENT OF PEDIATRIC CHOLESTATIC LIVER DISEASES SHIRE HUMAN GENETIC THERAPIES (US) 2026-05-06 EP disclosed
EP-4424363-B1 METHODS FOR INCREASING GROWTH IN PEDIATRIC SUBJECTS HAVING CHOLESTATIC LIVER DISEASE MIRUM PHARMACEUTICALS INC (US) 2026-04-29 EP disclosed
US-12599602-B2 Methods for treating cholestasis MIRUM PHARMACEUTICALS, INC. 2026-04-14 US disclosed
US-12576079-B2 Methods for treating cholestasis MIRUM PHARMACEUTICALS, INC. 2026-03-17 US disclosed
US-5965191-A TREATING WITH SALT AND AN ALKALI MATERIAL KABUSHIKI KAISHA KATAYAMA (JP) 1999-10-12 US disclosed
WO-1999012521-A1 NEW FOAM-FORMING PHARMACEUTICAL COMPOSITION ASTRA AKTIEBOLAG (SE) 1999-03-18 WO disclosed
WO-1999005987-A1 TOOTH WHITENING SYSTEM ANDERSON MICHAEL R (US) 1999-02-11 WO disclosed
EP-0813821-A1 PROCESSED FISH MEAT, FISH MEAT MATERIAL PREPARED BY USING THE SAME, AND PROCESS FOR PRODUCING PROCESSED FISH MEAT Kabushiki Kaisha Katayama (JP) 1997-12-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12599602-B2 Methods for treating cholestasis SLC10A1, SLC10A2, SLC10A6 LMNA 3099/4885L3MBTL1 3109/4885TDP1 3996/4885
US-12576079-B2 Methods for treating cholestasis SLC10A1, SLC10A2, SLC10A6 LMNA 2963/4885L3MBTL1 1199/4885TDP1 4586/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.