Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 4/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16149703 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRSOAT1FASNFAAH | |
| SCHEMBL9492045 | 0.93 | ALDH1A1 (0.41) | ALDH1A1TSHRSOAT1FASNFAAH | |
| SCHEMBL9492047 | 0.93 | ALDH1A1 (0.41) | ALDH1A1TSHRSOAT1FASNFAAH | |
| SCHEMBL732602 | 0.90 | ALDH1A1 (0.41) | ALDH1A1TSHRSOAT1FASNTRPV1 | |
| SCHEMBL20372249 | 0.90 | ALDH1A1 (0.41) | ALDH1A1TSHRSOAT1FASNTRPV1 | |
| SCHEMBL10282163 | 0.90 | ALDH1A1 (0.41) | ALDH1A1TSHRSOAT1FASNTRPV1 | |
| SCHEMBL732601 | 0.90 | ALDH1A1 (0.41) | ALDH1A1TSHRSOAT1FASNTRPV1 | |
| SCHEMBL2915027 | 0.88 | ALDH1A1 (0.64) | ALDH1A1TSHRSOAT1FASNFAAH | |
| SCHEMBL2915024 | 0.88 | ALDH1A1 (0.64) | ALDH1A1TSHRSOAT1FASNFAAH | |
| SCHEMBL14968886 | 0.88 | ALDH1A1 (0.64) | ALDH1A1TSHRSOAT1FASNFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745266-B2 | Indoline alkaloid compounds | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2017-08-29 | — | — | US | disclosed |
| US-20160060219-A1 | INDOLINE ALKALOID COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2016-03-03 | — | — | US | disclosed |
| WO-2014165548-A2 | INDOLINE ALKALOID COMPOUNDS | THE REGENTS OF THE UNIVERISITY OF COLORADO, A BODY CORPORATE (US) | 2014-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160060219-A1 | INDOLINE ALKALOID COMPOUNDS | INMT, IDO1, SRM | ALDH1A1 2629/4885TSHR 3843/4885SOAT1 2160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.