SCHEMBL16150283

SCHEMBL16150283

C1CCCC2NCCC2CC1

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MBTD1 Q05BQ5 3/20 0.39
L3MBTL3 Q96JM7 2/20 0.39
ALDH1A1 P00352 2/20 0.37
EPAS1 Q99814 1/20 0.36
MAPK1 P28482 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.33
PKM P14618 1/20 0.31
PRCP P42785 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24870211 1.00 MBTD1 (0.39) MBTD1L3MBTL3ALDH1A1EPAS1MAPK1
SCHEMBL2378409 1.00 MBTD1 (0.39) MBTD1L3MBTL3ALDH1A1EPAS1MAPK1
SCHEMBL4452609 0.97
SCHEMBL4450273 0.97
SCHEMBL17681496 0.97
SCHEMBL245244 0.97
SCHEMBL9047529 0.97
SCHEMBL30511 0.97
SCHEMBL1254524 0.97
SCHEMBL9279532 0.97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240024318-A1 SMARCA DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2024-01-25 US disclosed
CN-116710425-A Pharmaceutical agents for the treatment of disorders involving lannodine receptors 阿姆果制药有限公司 2023-09-05 CN disclosed
US-11679109-B2 SMARCA degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2023-06-20 US disclosed
EP-2970223-A1 NOVEL 5-HYDROXYTRYPTAMINE RECEPTOR 7 ACTIVITY MODULATORS AND THEIR METHOD OF USE Temple University Of The Commonwealth System Of Higher Education (US) 2016-01-20 EP disclosed
US-8916275-B2 Light emitting device material and light emitting device TORAY INDUSTRIES, INC. (JP) 2014-12-23 US disclosed
WO-2014164756-A1 NOVEL 5-HYDROXYTRYPTAMINE RECEPTOR 7 ACTIVITY MODULATORS AND THEIR METHOD OF USE TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2014-10-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240024318-A1 SMARCA DEGRADERS AND USES THEREOF SMARCA1, SMARCA2, SMARCC2 MBTD1 2562/4885L3MBTL3 2945/4885ALDH1A1 2230/4885
US-11679109-B2 SMARCA degraders and uses thereof SMARCA1, SMARCA2, SMARCC2 MBTD1 2562/4885L3MBTL3 2945/4885ALDH1A1 2230/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.