SCHEMBL16150672

SCHEMBL16150672

CCN(C(=O)c1ccncc1)c1cccc(C(=O)N(C(C)=O)c2c(Cl)cc(C(F)(C(F)(F)F)C(F)(F)F)cc2Br)c1OC

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MLYCD O95822 1/20 0.37
SLC2A1 P11166 2/20 0.33
GAA P10253 1/20 0.33
MCOLN3 Q8TDD5 1/20 0.33
GPBAR1 Q8TDU6 8/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17829477 0.93 MLYCD (0.37) MLYCDSLC2A1GAAMCOLN3GPBAR1
SCHEMBL16150584 0.89 MLYCD (0.40) MLYCDGAAMCOLN3
SCHEMBL16151164 0.84 MLYCD (0.38) MLYCDGAAMCOLN3GPBAR1MEN1
SCHEMBL29378569 0.84 MLYCD (0.38) MLYCDGAAMCOLN3GPBAR1MEN1
SCHEMBL17829475 0.82 MLYCD (0.39) MLYCD
SCHEMBL16863607 0.81 MLYCD (0.37) MLYCDGAAMCOLN3GPBAR1MEN1
SCHEMBL16150431 0.79 GPBAR1 (0.37) MLYCDGPBAR1
SCHEMBL14844565 0.78 GPBAR1 (0.42) MLYCDGPBAR1
SCHEMBL17829478 0.77 MLYCD (0.37) MLYCDGAAMCOLN3GPBAR1
SCHEMBL18356120 0.76 MLYCD (0.36) MLYCDSLC2A1GPBAR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2981519-B1 PROCESS FOR THE PREPARATION OF AMIDES FROM HINDERED ANILINES CONTAINING A PERHALOALKYL GROUP SYNGENTA PARTICIPATIONS AG (CH) 2018-08-01 EP disclosed
EP-2981519-B1 PROCESS FOR THE PREPARATION OF AMIDES FROM HINDERED ANILINES CONTAINING A PERHALOALKYL GROUP SYNGENTA PARTICIPATIONS AG (CH) 2018-08-01 EP disclosed
US-9598369-B2 Process for the preparation of amides from hindered anilines containing a perhaloalkyl group SYNGENTA PARTICIPATIONS AG (CH) 2017-03-21 US disclosed
US-9598369-B2 Process for the preparation of amides from hindered anilines containing a perhaloalkyl group SYNGENTA PARTICIPATIONS AG (CH) 2017-03-21 US disclosed
US-20160168097-A1 PROCESS FOR THE PREPARATION OF AMIDES FROM HINDERED ANILINES CONTAINING A PERHALOALKYL GROUP SYNGENTA PARTICIPATIONS AG (CH) 2016-06-16 US disclosed
US-20160168097-A1 PROCESS FOR THE PREPARATION OF AMIDES FROM HINDERED ANILINES CONTAINING A PERHALOALKYL GROUP SYNGENTA PARTICIPATIONS AG (CH) 2016-06-16 US disclosed
EP-2981519-A1 PROCESS FOR THE PREPARATION OF AMIDES FROM HINDERED ANILINES CONTAINING A PERHALOALKYL GROUP Syngenta Participations AG (CH) 2016-02-10 EP disclosed
WO-2014161850-A1 PROCESS FOR THE PREPARATION OF AMIDES FROM HINDERED ANILINES CONTAINING A PERHALOALKYL GROUP SYNGENTA PARTICIPATIONS AG (CH) 2014-10-09 WO disclosed
WO-2014161850-A1 PROCESS FOR THE PREPARATION OF AMIDES FROM HINDERED ANILINES CONTAINING A PERHALOALKYL GROUP SYNGENTA PARTICIPATIONS AG (CH) 2014-10-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160168097-A1 PROCESS FOR THE PREPARATION OF AMIDES FROM HINDERED ANILINES CONTAINING A PERHALOALKYL GROUP ABHD5, FADS1, PFAS MLYCD 1591/4885SLC2A1 2163/4885GAA 2424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.