SCHEMBL1615338

SCHEMBL1615338

Cc1ccc(O)c(N=Nc2ccccc2C)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.73
RAB9A P51151 2/20 0.73
FTO Q9C0B1 1/20 0.69
KMT2A Q03164 8/20 0.54
MAPT P10636 7/20 0.53
L3MBTL1 Q9Y468 4/20 0.53
MAPK1 P28482 4/20 0.53
THRB P10828 2/20 0.51
MPL P40238 1/20 0.50
HSP90AA1 P07900 1/20 0.50
CCR6 P51684 1/20 0.50
MEN1 O00255 6/20 0.49
HTT P42858 5/20 0.49
SMN1; SMN2 Q16637 5/20 0.49
TDP1 Q9NUW8 5/20 0.49
KDM4E B2RXH2 4/20 0.49
LMNA P02545 4/20 0.49
AGTR1 P30556 1/20 0.49
OPRK1 P41145 1/20 0.49
ALDH1A1 P00352 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11955367 1.00 NPC1 (0.73) NPC1RAB9AFTOKMT2AMAPT
SCHEMBL29377457 1.00 NPC1 (0.73) NPC1RAB9AFTOKMT2AMAPT
SCHEMBL11305364 0.89 FTO (0.73) NPC1RAB9AFTOKMT2AMAPT
SCHEMBL11305360 0.89 FTO (0.73) NPC1RAB9AFTOKMT2AMAPT
SCHEMBL7913514 0.86 NPC1 (0.80) NPC1RAB9AFTOKMT2AMAPT
SCHEMBL8204503 0.86 NPC1 (0.80) NPC1RAB9AFTOKMT2AMAPT
SCHEMBL13290672 0.82 KMT2A (0.73) NPC1RAB9AFTOKMT2AMAPT
SCHEMBL14597256 0.82 KMT2A (0.73) NPC1RAB9AFTOKMT2AMAPT
SCHEMBL1275967 0.81 FTO (1.00) NPC1RAB9AFTOKMT2AMAPT
SCHEMBL1275966 0.81 FTO (1.00) NPC1RAB9AFTOKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2582520-B2 Insertion tube INFIANA GERMANY GMBH & CO KG (DE) 2019-01-16 EP disclosed
EP-2747973-B1 LINER HOSE FOR SEWERS REHABILITATION STARK KURT (DE) 2018-01-24 EP disclosed
US-8794269-B2 Multi-layer film permeable to UV radiation HUHTAMAKI FILMS GERMANY GMBH & CO. KG (DE) 2014-08-05 US disclosed
EP-2747973-A1 INSERT HOSE FOR SEWER REHABILITATION Stark, Kurt (DE) 2014-07-02 EP disclosed
EP-2582520-B1 MULTI-LAYER FILM PERMEABLE TO UV RADIATION HUHTAMAKI FILMS GERMANY GMBH (DE) 2014-04-30 EP disclosed
US-20130126029-A1 MULTI-LAYER FILM PERMEABLE TO UV RADIATION HUHTAMAKI FILMS GERMANY GMBH & CO. KG. (DE) 2013-05-23 US disclosed
EP-2582520-A1 MULTI-LAYER FILM PERMEABLE TO UV RADIATION Huhtamaki Films Germany GmbH & Co. KG (DE) 2013-04-24 EP disclosed
WO-2013026568-A1 INSERT HOSE FOR SEWER REHABILITATION HUHTAMAKI FILMS GERMANY GMBH & CO. KG (DE) 2013-02-28 WO disclosed
EP-2379625-B1 UV AND LIGHT PROTECTIVE FILM HUHTAMAKI FORCHHEIM (DE) 2013-02-20 EP disclosed
US-8361580-B2 UV light and protective film HUHTAMAKI FORSCHHEIM, ZWEIGNIEDERLASSUNG DER HUHTAMAKI DEUTSCHLAND GMBH & CO. KG (DE) 2013-01-29 US disclosed
US-7781571-B2 Ophthalmic lens materials containing chromophores that absorb both UV and short wavelength visible light ALCON, INC. (CH) 2010-08-24 US disclosed
US-7781571-B2 Ophthalmic lens materials containing chromophores that absorb both UV and short wavelength visible light ALCON, INC. (CH) 2010-08-24 US disclosed
WO-2010075946-A1 UV AND LIGHT PROTECTIVE FILM HUHTAMAKI FORCHHEIM, ZWEIGNIEDERLASSUNG DER HUHTAMAKI DEUTSCHLAND GMBH & CO. KG (DE) 2010-07-08 WO disclosed
EP-0674684-B1 POLYMERISABLE YELLOW DYES AND THEIR USE IN OPHTHALMIC LENSES ALCON LAB INC (US) 1999-01-27 EP disclosed
US-5662707-A Polymerizable yellow dyes and their use in ophthalmic lenses ALCON LABORATORIES, INC. (US) 1997-09-02 US disclosed
US-5543504-A REDUCE INTENSITY OF BLUE LIGHT ALCON LABORATORIES, INC. (US) 1996-08-06 US disclosed
US-5528322-A AZO DYE GROUP-CONTAINING ACRYLATE AND METHACRYLATE MONOMERS ALCON LABORATORIES, INC. (US) 1996-06-18 US disclosed
US-5470932-A Polymerizable yellow dyes and their use in opthalmic lenses ALCON LABORATORIES, INC. (US) 1995-11-28 US disclosed
EP-0674684-A1 POLYMERISABLE YELLOW DYES AND THEIR USE IN OPHTHALMIC LENSES ALCON LABORATORIES, INC. (US) 1995-10-04 EP disclosed
WO-1995011279-A1 POLYMERISABLE YELLOW DYES AND THEIR USE IN OPHTHALMIC LENSES ALCON LABORATORIES, INC. (US) 1995-04-27 WO disclosed