Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HSD17B13 | Q7Z5P4 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16006518 | 0.85 | MAPT (0.44) | KMT2AMAPTNPC1RAB9ACHUK | |
| SCHEMBL17697579 | 0.84 | CYP3A4 (0.41) | KMT2AMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17697582 | 0.84 | NR3C2 (0.34) | KMT2AMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19788775 | 0.83 | MAPT (0.43) | KMT2AMAPTNPC1RAB9ACHUK | |
| SCHEMBL17697553 | 0.82 | CASP1 (0.40) | KMT2AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL24997637 | 0.82 | KMT2A (0.42) | KMT2AMAPTNPC1RAB9ACHUK | |
| SCHEMBL17621602 | 0.81 | SMN1; SMN2 (0.37) | KMT2AMAPTNPC1SMN1; SMN2MEN1 | |
| SCHEMBL17621512 | 0.81 | CASP1 (0.34) | KMT2AMAPTNPC1SMN1; SMN2MEN1 | |
| SCHEMBL17621574 | 0.80 | ALDH1A1 (0.36) | KMT2AMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17621604 | 0.79 | KMT2A (0.43) | KMT2AMAPTHSD17B13LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140303164-A1 | THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. | 2014-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140303164-A1 | THERAPEUTIC COMPOUNDS | HAVCR2, SARS1, G6PD | KMT2A 4702/4885MAPT 1618/4885NPC1 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.