Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16006445 | 0.88 | PDK1 (0.33) | KMT2AMAPTNPC1RAB9AS1PR2 | |
| SCHEMBL19788777 | 0.85 | ALDH1A1 (0.41) | KMT2AMAPTNPC1RAB9AS1PR2 | |
| SCHEMBL16006518 | 0.84 | MAPT (0.44) | KMT2AMAPTNPC1RAB9ACHUK | |
| SCHEMBL20078890 | 0.83 | MAPT (0.33) | KMT2AMAPTNPC1S1PR2SMN1; SMN2 | |
| SCHEMBL25639161 | 0.82 | CYP3A4 (0.39) | KMT2AMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19788775 | 0.82 | MAPT (0.43) | KMT2AMAPTNPC1RAB9ACHUK | |
| SCHEMBL16158000 | 0.82 | KMT2A (0.43) | KMT2AMAPTNPC1RAB9ACHUK | |
| SCHEMBL22885997 | 0.78 | — | — | |
| SCHEMBL20079062 | 0.77 | MEN1 (0.50) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL25644750 | 0.77 | KDM4E (0.39) | KMT2ANPC1RAB9ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230038823-A1 | CAPSID INHIBITORS FOR THE TREATMENT OF HIV | GILEAD SCIENCES, INC. (US) | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230038823-A1 | CAPSID INHIBITORS FOR THE TREATMENT OF HIV | HAVCR2, MAVS, CD4 | KMT2A 3427/4885MAPT 170/4885NPC1 50/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.