SCHEMBL16158461

SCHEMBL16158461

CC(C)C(C)(C)OB(O)c1cc(C(C)(C)C)ccc1-c1ccc(C(C)(C)C)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.39
AKR1C2 P52895 1/20 0.39
GPR84 Q9NQS5 1/20 0.34
ALDH1A1 P00352 2/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
PLA2G1B P04054 1/20 0.33
NFKB1 P19838 1/20 0.33
CASP3 P42574 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ATG4B Q9Y4P1 1/20 0.33
EGFR P00533 1/20 0.33
DHODH Q02127 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10015450 0.78 AKR1C3 (0.41) AKR1C3AKR1C2GPR84ALDH1A1NPC1
SCHEMBL31026102 0.78 AKR1C3 (0.41) AKR1C3AKR1C2GPR84ALDH1A1NPC1
SCHEMBL17613263 0.70
SCHEMBL29956444 0.65 NPC1 (0.41) GPR84ALDH1A1NPC1RAB9APLA2G1B
SCHEMBL21102244 0.65 NPC1 (0.41) GPR84ALDH1A1NPC1RAB9APLA2G1B
SCHEMBL5952628 0.64 ORAI1 (0.34) ALDH1A1NFKB1
SCHEMBL17358859 0.63 EGFR (0.48) AKR1C3AKR1C2GPR84ALDH1A1NPC1
SCHEMBL25677940 0.62 LMNA (0.40) ALDH1A1NPC1RAB9ALMNATP53
SCHEMBL5952636 0.62 TRPV6 (0.38) ALDH1A1ALOX15LMNA
SCHEMBL19318456 0.62 EGFR (0.50) AKR1C3AKR1C2ALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014163211-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2014-10-09 WO disclosed