Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21102244 | 1.00 | NPC1 (0.41) | NPC1RAB9AKMT2AMEN1NR2F2 | |
| SCHEMBL29271176 | 0.83 | RXRB (0.40) | NPC1RAB9AKMT2AMEN1NR2F2 | |
| SCHEMBL24910022 | 0.83 | KIF11 (0.50) | KIF11ALDH1A1KDM4ETSHR | |
| SCHEMBL10015450 | 0.81 | AKR1C3 (0.41) | NPC1RAB9AKMT2AMEN1NR2F2 | |
| SCHEMBL25677940 | 0.81 | LMNA (0.40) | NPC1RAB9AKMT2AMEN1NR2F2 | |
| SCHEMBL31026102 | 0.81 | AKR1C3 (0.41) | NPC1RAB9AKMT2AMEN1NR2F2 | |
| SCHEMBL4145743 | 0.79 | MGLL (0.54) | ALDH1A1SMN1; SMN2HDAC6 | |
| SCHEMBL29825386 | 0.79 | MGLL (0.54) | ALDH1A1SMN1; SMN2HDAC6 | |
| SCHEMBL21933 | 0.79 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1SMN1; SMN2HDAC6 | |
| SCHEMBL29838597 | 0.79 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1SMN1; SMN2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |