SCHEMBL161608

SCHEMBL161608

COc1ccc(CCSC(=S)c2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
LTA4H P09960 1/20 0.50
ALDH1A1 P00352 5/20 0.47
KDM4E B2RXH2 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
MAPT P10636 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
LMNA P02545 2/20 0.47
MAPK1 P28482 1/20 0.46
TAAR1 Q96RJ0 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
ATM Q13315 1/20 0.46
TDP1 Q9NUW8 2/20 0.45
GAA P10253 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL163065 0.85 NOS1 (0.52) NPC1RAB9AALDH1A1CYP1A2CYP3A4
SCHEMBL7582816 0.81 NPC1 (0.50) NPC1RAB9ALTA4HALDH1A1KDM4E
SCHEMBL6581242 0.76 NPC1 (0.59) NPC1RAB9ALTA4HALDH1A1KDM4E
SCHEMBL2355634 0.76 LTA4H (0.75) NPC1RAB9ALTA4HTAAR1KMT2A
SCHEMBL28299804 0.75 LDHA (0.47) NPC1RAB9ALTA4HALDH1A1KDM4E
SCHEMBL16229992 0.74 HDAC3 (0.48) NPC1RAB9AALDH1A1CYP1A2CYP3A4
Phenethylamine SCHEMBL22129843 0.73 TAAR1 (0.84) LTA4HTAAR1SMN1; SMN2
SCHEMBL5632470 0.73 LTA4H (0.69) NPC1RAB9ALTA4HALDH1A1TAAR1
SCHEMBL13097712 0.72 MEN1 (0.39) ALDH1A1KDM4ECYP1A2CYP3A4CYP2D6
SCHEMBL27563914 0.72 LTA4H (0.58) NPC1RAB9ALTA4HCYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747339-A1 INDUSTRIAL GEAR LUBRICANT The Lubrizol Corporation (US) 2026-05-27 EP disclosed
EP-4583933-A1 FLUOROPOLYMER MEDICAL DEVICES Unomedical A/S (DK) 2025-07-16 EP disclosed
EP-4583934-A1 MEDICAL DEVICES Unomedical A/S (DK) 2025-07-16 EP disclosed
WO-2025019655-A1 INDUSTRIAL GEAR LUBRICANT THE LUBRIZOL CORPORATION (US) 2025-01-23 WO disclosed
EP-4376912-A1 INTERMITTENT CATHETERS ConvaTec Limited (GB) 2024-06-05 EP disclosed
WO-2024052192-A1 FLUOROPOLYMER MEDICAL DEVICES UNOMEDICAL A/S (DK) 2024-03-14 WO disclosed
WO-2024052193-A1 MEDICAL DEVICES UNOMEDICAL A/S (DK) 2024-03-14 WO disclosed
US-20230383102-A1 RUBBER COMPOSITION, VULCANIZED PRODUCT, AND VULCANIZED MOLDED ARTICLE DENKA COMPANY LIMITED (JP) 2023-11-30 US disclosed
WO-2023007131-A1 INTERMITTENT CATHETERS CONVATEC LIMITED (GB) 2023-02-02 WO disclosed
EP-3408016-A1 POLYMERIC DISPERSANTS CONTAINING MULTI-AMINE GROUPS WITH IMPROVED CHEMICAL AND THERMAL STABILITY Lubrizol Advanced Materials, Inc. (US) 2018-12-05 EP disclosed
WO-2008145613-A1 GRAFT COPOLYMER AND COMPOSITIONS THEREOF LUBRIZOL LIMITED (GB) 2008-12-04 WO disclosed
WO-2007127615-A2 STAR POLYMER LUBRICATING COMPOSITION THE LUBRIZOL CORPORATION (US) 2007-11-08 WO disclosed
WO-2007127660-A1 STAR POLYMER LUBRICATING COMPOSITION THE LUBRIZOL CORPORATION (US) 2007-11-08 WO disclosed
WO-2007127663-A2 STAR POLYMER LUBRICATING COMPOSITION THE LUBRIZOL CORPORATION (US) 2007-11-08 WO disclosed
EP-1833852-A1 PROCESS FOR PREPARING POLYMERS AND COMPOSITIONS THEREOF THE LUBRIZOL CORPORATION (US) 2007-09-19 EP disclosed
EP-1833868-A2 STAR POLYMERS AND COMPOSITIONS THEREOF THE LUBRIZOL CORPORATION (US) 2007-09-19 EP disclosed
WO-2006047398-A2 STAR POLYMERS AND COMPOSITIONS THEREOF THE LUBRIZOL CORPORATION (US) 2006-05-04 WO disclosed
WO-2006047393-A1 PROCESS FOR PREPARING POLYMERS AND COMPOSITIONS THEREOF THE LUBRIZOL CORPORATION (US) 2006-05-04 WO disclosed
EP-0910587-A1 POLYMERIZATION WITH LIVING CHARACTERISTICS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-04-28 EP disclosed
WO-1998001478-A1 POLYMERIZATION WITH LIVING CHARACTERISTICS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-01-15 WO disclosed