SCHEMBL28299804

SCHEMBL28299804

COc1ccc(CC(C)SC(=S)c2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.47
SLC6A4 P31645 1/20 0.46
LTA4H P09960 1/20 0.45
PPARG P37231 1/20 0.44
PPARA Q07869 1/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
SIGMAR1 Q99720 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
KDM4E B2RXH2 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
ALDH1A1 P00352 2/20 0.42
MAPK1 P28482 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2770805 0.86 TRPA1 (0.44) SLC6A4NPC1RAB9ASIGMAR1
SCHEMBL1524998 0.77 L3MBTL1 (0.48) LTA4HNPC1RAB9ASMN1; SMN2MEN1
SCHEMBL2520394 0.76 KMT2A (0.44) SLC6A4NPC1RAB9ASIGMAR1MEN1
SCHEMBL21633293 0.76 MAPT (0.42) SLC6A4PPARGPPARANPC1RAB9A
Benzoic Acid SCHEMBL28685771 0.75 LDHA (0.57) LDHAPPARGPPARANPC1RAB9A
SCHEMBL161608 0.75 NPC1 (0.51) LTA4HNPC1RAB9ASMN1; SMN2MEN1
SCHEMBL8430509 0.73 LTA4H (0.56) LDHASLC6A4LTA4HPPARGPPARA
SCHEMBL31561610 0.73 LDHA (0.58) LDHASLC6A4LTA4HPPARGPPARA
SCHEMBL18508067 0.72 HDAC3 (0.39) NPC1RAB9ASMN1; SMN2CES2CES1
SCHEMBL22204619 0.72 TRPA1 (0.38) NPC1RAB9ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109762625-A Poly- (methyl) the acrylate brush polymer of polydialkysiloxane for lubricant additive application 雅富顿化学公司 2019-05-17 CN disclosed