SCHEMBL161628

SCHEMBL161628

Cc1ccc(S(=O)(=O)C=CC#N)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 1.00
MAPT P10636 5/20 1.00
TDP1 Q9NUW8 4/20 1.00
HPGD P15428 3/20 1.00
KMT2A Q03164 3/20 1.00
NPC1 O15118 2/20 1.00
NFKB1 P19838 2/20 1.00
RAB9A P51151 2/20 1.00
MEN1 O00255 2/20 1.00
TP53 P04637 2/20 1.00
CYP1A2 P05177 2/20 1.00
CYP3A4 P08684 2/20 1.00
CYP2D6 P10635 2/20 1.00
CYP2C9 P11712 2/20 1.00
MAPK1 P28482 2/20 1.00
CYP2C19 P33261 2/20 1.00
HSD17B10 Q99714 2/20 1.00
S100A4 P26447 1/20 1.00
MTOR P42345 1/20 1.00
NFKB2 Q00653 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20774334 1.00 ALDH1A1 (1.00) ALDH1A1MAPTTDP1HPGDKMT2A
SCHEMBL161627 1.00 ALDH1A1 (1.00) ALDH1A1MAPTTDP1HPGDKMT2A
SCHEMBL11837169 0.86 MAPT (0.74) ALDH1A1MAPTTDP1HPGDKMT2A
SCHEMBL11837176 0.86 MAPT (0.74) ALDH1A1MAPTTDP1HPGDKMT2A
SCHEMBL11841569 0.82 ALDH1A1 (0.67) ALDH1A1MAPTTDP1HPGDKMT2A
SCHEMBL2578234 0.81 TLR9 (1.00) ALDH1A1MAPTTDP1HPGDKMT2A
SCHEMBL2578236 0.81 TLR9 (1.00) ALDH1A1MAPTTDP1HPGDKMT2A
SCHEMBL14141134 0.81 ALDH1A1 (0.68) ALDH1A1MAPTTDP1HPGDKMT2A
SCHEMBL20774379 0.81 ALDH1A1 (0.68) ALDH1A1MAPTTDP1HPGDKMT2A
SCHEMBL20774381 0.81 ALDH1A1 (0.68) ALDH1A1MAPTTDP1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 587 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035753-A1 METHODS OF DETERMINING BACTERIA AND MANUFACTURING A FIBROUS WEB AND TOOLS AND USES RELATED THERETO KEMIRA OYJ (FI) 2026-02-05 US claimed
EP-4662200-A1 METHOD FOR PREPARING ARYLVINYLSULPHONES Kemira OYJ (FI) 2025-12-17 EP claimed
EP-3528776-B1 REDUCED-ETHANOL MOUTH RINSE FORMULATIONS KENVUE BRANDS LLC (US) 2025-11-26 EP claimed
US-20250059074-A1 ANTIMICROBIAL SYSTEM AND METHOD KEMIRA OYJ (FI) 2025-02-20 US claimed
EP-4214190-B1 METHOD FOR PREPARING ARYLVINYLSULPHONES KEMIRA OYJ (FI) 2025-02-19 EP claimed
US-20240383784-A1 ANTIMICROBIAL SYSTEM AND METHOD KEMIRA OYJ (FI) 2024-11-21 US claimed
EP-4447685-A1 ANTIMICROBIAL SYSTEM AND METHOD Kemira OYJ (FI) 2024-10-23 EP claimed
EP-4447666-A1 ANTIMICROBIAL SYSTEM AND METHOD Kemira OYJ (FI) 2024-10-23 EP claimed
US-12114659-B2 Method for controlling growth of microorganisms and/or biofilms in an industrial process KEMIRA OYJ (FI) 2024-10-15 US claimed
WO-2024199939-A1 METHOD FOR PREPARING ARYLVINYLSULPHONES KEMIRA OYJ (FI) 2024-10-03 WO claimed
WO-2006081327-A2 SMALL MOLECULES THAT REDUCE FUNGAL GROWTH UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) 2006-08-03 WO claimed
US-20040241166-A1 Screening by contacting inhibitor (sulindac) with endothelial cells activated by blood platelets, and determining secretion of MCP-1 (Monocyte chemoattractant protein-1); for treatment and prevention of atherosclerosis PROCORDE GMBH (DE) 2004-12-02 US claimed
EP-1372689-B1 USE OF IKK-BETA INHIBITORS AND METHOD FOR DISCOVERY OF SAID INHIBITORS PROCORDE GMBH (DE) 2004-07-14 EP claimed
WO-1997007683-A1 LOW-NITRITE COMPOSITION FOR CURING MEAT AND PROCESS FOR PREPARING LOW-NITRITE CURED MEAT PRODUCTS FOOD BIOTEK CORPORATION (CA) 1997-03-06 WO claimed
EP-0122062-B1 METHOD FOR PRESERVATION OF MEAT PRODUCTS STAUFFER CHEMICAL COMPANY (US) 1988-05-18 EP claimed
EP-0093792-B1 METHOD FOR CONTROLLING ALGAE STAUFFER CHEMICAL COMPANY (US) 1986-09-10 EP claimed
EP-0122062-A2 Method for preservation of meat products STAUFFER CHEMICAL COMPANY (US) 1984-10-17 EP claimed
US-4443484-A INHIBITING GROWTH OF CLOSTRIDIUM, 3-(4-TOLYLSULFONYL)ACRYLONITRILE, ALKALI NITRITE STAUFFER CHEMICAL COMPANY (US) 1984-04-17 US claimed
EP-0093792-A1 Method for controlling algae STAUFFER CHEMICAL COMPANY (US) 1983-11-16 EP claimed
US-4331681-A Method for controlling algae STAUFFER CHEMICAL COMPANY (US) 1982-05-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035753-A1 METHODS OF DETERMINING BACTERIA AND MANUFACTURING A FIBROUS WEB AND TOOLS AND USES RELATED THERETO POLL, UROD, RNGTT ALDH1A1 2058/4885MAPT 228/4885TDP1 162/4885
US-20250059074-A1 ANTIMICROBIAL SYSTEM AND METHOD HAO2, APEH, CHCHD6 ALDH1A1 577/4885MAPT 4815/4885TDP1 4387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.