SCHEMBL161627

SCHEMBL161627

Cc1ccc(S(=O)(=O)/C=C/C#N)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 1.00
MAPT P10636 5/20 1.00
TDP1 Q9NUW8 4/20 1.00
HPGD P15428 3/20 1.00
KMT2A Q03164 3/20 1.00
NPC1 O15118 2/20 1.00
NFKB1 P19838 2/20 1.00
RAB9A P51151 2/20 1.00
MEN1 O00255 2/20 1.00
TP53 P04637 2/20 1.00
CYP1A2 P05177 2/20 1.00
CYP3A4 P08684 2/20 1.00
CYP2D6 P10635 2/20 1.00
CYP2C9 P11712 2/20 1.00
MAPK1 P28482 2/20 1.00
CYP2C19 P33261 2/20 1.00
HSD17B10 Q99714 2/20 1.00
S100A4 P26447 1/20 1.00
MTOR P42345 1/20 1.00
NFKB2 Q00653 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL161628 1.00 ALDH1A1 (1.00) ALDH1A1MAPTTDP1HPGDKMT2A
SCHEMBL20774334 1.00 ALDH1A1 (1.00) ALDH1A1MAPTTDP1HPGDKMT2A
SCHEMBL11837169 0.86 MAPT (0.74) ALDH1A1MAPTTDP1HPGDKMT2A
SCHEMBL11837176 0.86 MAPT (0.74) ALDH1A1MAPTTDP1HPGDKMT2A
SCHEMBL11841569 0.82 ALDH1A1 (0.67) ALDH1A1MAPTTDP1HPGDKMT2A
SCHEMBL2578234 0.81 TLR9 (1.00) ALDH1A1MAPTTDP1HPGDKMT2A
SCHEMBL2578236 0.81 TLR9 (1.00) ALDH1A1MAPTTDP1HPGDKMT2A
SCHEMBL14141134 0.81 ALDH1A1 (0.68) ALDH1A1MAPTTDP1HPGDKMT2A
SCHEMBL20774379 0.81 ALDH1A1 (0.68) ALDH1A1MAPTTDP1HPGDKMT2A
SCHEMBL20774381 0.81 ALDH1A1 (0.68) ALDH1A1MAPTTDP1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1942 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026087695-A1 TREATMENT FOR METABOLIC DISORDER SAPREME TECHNOLOGIES B.V. (NL) 2026-04-30 WO claimed
WO-2026087680-A1 TREATMENT FOR CARDIOVASCULAR DISEASE SAPREME TECHNOLOGIES B.V. (NL) 2026-04-30 WO claimed
US-20260091162-A1 SPRAYABLE POLYMERIC SCAFFOLD LOADED WITH INFLAMMASOME-INHIBITING LIPID NANORODS FOR ANTI-INFLAMMATION THERAPY KULKARNI ASHISH (US) 2026-04-02 US claimed
US-20260035753-A1 METHODS OF DETERMINING BACTERIA AND MANUFACTURING A FIBROUS WEB AND TOOLS AND USES RELATED THERETO KEMIRA OYJ (FI) 2026-02-05 US claimed
EP-4662200-A1 METHOD FOR PREPARING ARYLVINYLSULPHONES Kemira OYJ (FI) 2025-12-17 EP claimed
US-20250375534-A1 COMPLEXES FOR DELIVERY OF NUCLEIC ACIDS BioNTech SE (DE) 2025-12-11 US claimed
US-20250364144-A1 CANCER PHARMACOPREVENTION THROUGH ARTIFICIAL INTELLIGENCE UNIV ILLINOIS (US) 2025-11-27 US claimed
EP-3528776-B1 REDUCED-ETHANOL MOUTH RINSE FORMULATIONS KENVUE BRANDS LLC (US) 2025-11-26 EP claimed
US-20250262241-A1 METHODS TO IMPROVE STABILITY OF VIRUS TRANSDUCTION OF y8 T CELLS AND APPLICATIONS THEREOF UNICET BIOTECH CO LLC (CN) 2025-08-21 US claimed
US-20250235456-A1 METHODS OF USE FOR AZA-QUINAZOLINE COMPOUNDS IAMBIC THERAPEUTICS, INC. 2025-07-24 US claimed
EP-2316413-A2 Compositions comprising an nfkb-inhibitor and a non-retinoid collagen promoter Johnson and Johnson Consumer Companies, Inc. (US) 2011-05-04 EP claimed
US-20110081431-A1 COMPOSITIONS COMPRISING AN NFkB-INHIBITOR AND A NON-RETINOID COLLAGEN PROMOTER KENVUE BRANDS LLC 2011-04-07 US claimed
US-20110081430-A1 COMPOSITIONS COMPRISING AN NFkB-INHIBITOR AND A TROPOELASTIN PROMOTER JOHNSON & JOHNSON CONSUMER COMPANIES, INC. 2011-04-07 US claimed
US-20110081433-A1 COMPOSITIONS COMPRISING AN ANTI-INFLAMMATORY BLEND JOHNSON & JOHNSON CONSUMER INC. 2011-04-07 US claimed
US-20090082371-A1 Treatment of Viral Disease and Cancer With Nf-kappaB Inhibitors LU ZHIMIN 2009-03-26 US claimed
WO-2006109196-A2 TRANSGENIC MOUSE MODELS OF HEPATITIS C VIRUS (HCV) AND IDENTIFICATION OF HCV THERAPEUTICS TRIPEP AB (SE) 2006-10-19 WO claimed
US-20060194769-A1 Small molecules that reduce fungal growth UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) 2006-08-31 US claimed
WO-2006081327-A2 SMALL MOLECULES THAT REDUCE FUNGAL GROWTH UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) 2006-08-03 WO claimed
US-20040241166-A1 Screening by contacting inhibitor (sulindac) with endothelial cells activated by blood platelets, and determining secretion of MCP-1 (Monocyte chemoattractant protein-1); for treatment and prevention of atherosclerosis PROCORDE GMBH (DE) 2004-12-02 US claimed
EP-1372689-B1 USE OF IKK-BETA INHIBITORS AND METHOD FOR DISCOVERY OF SAID INHIBITORS PROCORDE GMBH (DE) 2004-07-14 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060194769-A1 Small molecules that reduce fungal growth ERG28, DPM1, CYP51A1 ALDH1A1 2931/4885MAPT 1481/4885TDP1 3838/4885
US-20110081431-A1 COMPOSITIONS COMPRISING AN NFkB-INHIBITOR AND A NON-RETINOID COLLAGEN PROMOTER NFKBIA, NFRKB, NFKB1 ALDH1A1 2842/4885MAPT 2768/4885TDP1 1199/4885
US-20250262241-A1 METHODS TO IMPROVE STABILITY OF VIRUS TRANSDUCTION OF y8 T CELLS AND APPLICATIONS THEREOF CD4, NFATC1, ICOS ALDH1A1 4618/4885MAPT 1318/4885TDP1 2134/4885
US-20250375534-A1 COMPLEXES FOR DELIVERY OF NUCLEIC ACIDS TLR3, TLR9, SARNP ALDH1A1 4446/4885MAPT 3674/4885TDP1 1427/4885
US-20090082371-A1 Treatment of Viral Disease and Cancer With Nf-kappaB Inhibitors RELA, NFKBIA, NFKB1 ALDH1A1 1659/4885MAPT 3202/4885TDP1 1101/4885
US-20250235456-A1 METHODS OF USE FOR AZA-QUINAZOLINE COMPOUNDS AZI2, TPMT, HDAC10 ALDH1A1 713/4885MAPT 4100/4885TDP1 506/4885
US-20260035753-A1 METHODS OF DETERMINING BACTERIA AND MANUFACTURING A FIBROUS WEB AND TOOLS AND USES RELATED THERETO POLL, UROD, RNGTT ALDH1A1 2058/4885MAPT 228/4885TDP1 162/4885
US-20110081430-A1 COMPOSITIONS COMPRISING AN NFkB-INHIBITOR AND A TROPOELASTIN PROMOTER NFKBIA, NFKB1, NFKB2 ALDH1A1 2391/4885MAPT 702/4885TDP1 71/4885
US-20260091162-A1 SPRAYABLE POLYMERIC SCAFFOLD LOADED WITH INFLAMMASOME-INHIBITING LIPID NANORODS FOR ANTI-INFLAMMATION THERAPY NLRP3, NLRP1, IL1B ALDH1A1 1965/4885MAPT 484/4885TDP1 2703/4885
US-20110081433-A1 COMPOSITIONS COMPRISING AN ANTI-INFLAMMATORY BLEND NFKBIA, NFKB2, NFKB1 ALDH1A1 4161/4885MAPT 374/4885TDP1 2135/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.