SCHEMBL16163129

SCHEMBL16163129

CCCCCCP(=O)(O)CC(CC)P(=O)(O)CCCCCC

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 3/20 0.48
LPAR2 Q9HBW0 1/20 0.48
PLA2G2D Q9UNK4 1/20 0.45
TRPM8 Q7Z2W7 9/20 0.43
CETP P11597 1/20 0.41
FDPS P14324 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16163412 0.98 LPAR3 (0.45) LPAR3LPAR2PLA2G2DTRPM8CETP
SCHEMBL16163356 0.93 GABBR2 (0.47) LPAR3LPAR2PLA2G2DTRPM8FDPS
SCHEMBL16163315 0.88 LPAR3 (0.47) LPAR3LPAR2PLA2G2DTRPM8CETP
SCHEMBL16163279 0.86 LPAR3 (0.44) LPAR3LPAR2PLA2G2DTRPM8FDPS
SCHEMBL16163303 0.85 LPAR3 (0.53) LPAR3LPAR2PLA2G2DTRPM8FDPS
SCHEMBL16163115 0.81 GCLC (0.36) LPAR3LPAR2PLA2G2DFDPS
SCHEMBL16163194 0.80 GABBR2 (0.46) LPAR3LPAR2PLA2G2DFDPS
SCHEMBL339376 0.77 LPAR3 (0.47) LPAR3LPAR2PLA2G2DTRPM8
SCHEMBL11434237 0.77 LPAR3 (0.56) LPAR3LPAR2FDPS
SCHEMBL3797655 0.77 LPAR3 (0.56) LPAR3LPAR2FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2791152-B1 MIXTURES OF DIPHOSPHINIC ACIDS AND DIALKYLPHOSPHINIC ACIDS, A PROCESS FOR THE PREPARATION THEREOF AND THE USE THEREOF CLARIANT INT LTD (CH) 2018-11-07 EP claimed
EP-2791149-B1 MIXTURES OF DIPHOSPHINIC ACIDS AND ALKYLPHOSPHINIC ACIDS, A PROCESS FOR THE PREPARATION THEREOF AND THE USE THEREOF CLARIANT INT LTD (CH) 2017-06-14 EP claimed
US-20150005421-A1 Mixtures Of Diphosphinic Acids And Dialkylphosphinic Acids, A Process For The Preparation Thereof And The Use Thereof CLARIANT FINANCE (BVI) LIMITED (VG) 2015-01-01 US claimed
US-20140329933-A1 Mixtures Of Diphosphinic Acids And Alkylphosphinic Acids, A Process For The Preparation Thereof And The Use Thereof CLARIANT INTERNATIONAL LTD. (CH) 2014-11-06 US claimed
US-20140309339-A1 Mixtures Of Diphosphinic Acids And Alkylphosphinic Acids, A Process For The Preparation Thereof And The Use Thereof CLARIANT FINANCE (BVI) LIMITED (VG) 2014-10-16 US claimed
US-20180030355-A1 Mixtures Of Diphosphinic Acids And Alkylphosphinic Acids, A Process For The Preparation Thereof And The Use Thereof CLARIANT INTERNATIONAL LTD. (CH) 2018-02-01 US disclosed
US-20170313942-A1 Mixtures Of Diphosphinic Acids And Dialkylphosphinic Acids, A Process For The Preparation Thereof And The Use Thereof CLARIANT INTERNATIONAL LTD. (CH) 2017-11-02 US disclosed
EP-2791149-B1 MIXTURES OF DIPHOSPHINIC ACIDS AND ALKYLPHOSPHINIC ACIDS, A PROCESS FOR THE PREPARATION THEREOF AND THE USE THEREOF CLARIANT INT LTD (CH) 2017-06-14 EP disclosed
US-20150005421-A1 Mixtures Of Diphosphinic Acids And Dialkylphosphinic Acids, A Process For The Preparation Thereof And The Use Thereof CLARIANT FINANCE (BVI) LIMITED (VG) 2015-01-01 US disclosed
US-20140329933-A1 Mixtures Of Diphosphinic Acids And Alkylphosphinic Acids, A Process For The Preparation Thereof And The Use Thereof CLARIANT INTERNATIONAL LTD. (CH) 2014-11-06 US disclosed
US-20140309339-A1 Mixtures Of Diphosphinic Acids And Alkylphosphinic Acids, A Process For The Preparation Thereof And The Use Thereof CLARIANT FINANCE (BVI) LIMITED (VG) 2014-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180030355-A1 Mixtures Of Diphosphinic Acids And Alkylphosphinic Acids, A Process For The Preparation Thereof And The Use Thereof PHOSPHO1, ENPP2, INPPL1 LPAR3 32/4885LPAR2 25/4885PLA2G2D 82/4885
US-20170313942-A1 Mixtures Of Diphosphinic Acids And Dialkylphosphinic Acids, A Process For The Preparation Thereof And The Use Thereof C3AR1, DCPS, ENPP2 LPAR3 48/4885LPAR2 33/4885PLA2G2D 255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.