SCHEMBL16163115

SCHEMBL16163115

CCCP(=O)(O)CC(CC)P(=O)(O)CCC

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GCLC P48506 1/20 0.36
PLA2G2D Q9UNK4 1/20 0.33
GABBR2 O75899 1/20 0.32
GABRR1 P24046 1/20 0.32
GABBR1 Q9UBS5 1/20 0.32
FDPS P14324 2/20 0.32
LAP3 P28838 1/20 0.32
METAP1 P53582 1/20 0.31
LPAR3 Q9UBY5 3/20 0.31
LPAR2 Q9HBW0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16163303 0.88 LPAR3 (0.53) PLA2G2DFDPSLPAR3LPAR2
SCHEMBL19455883 0.84 FDPS (0.39) PLA2G2DFDPSLAP3METAP1LPAR3
SCHEMBL16163356 0.84 GABBR2 (0.47) PLA2G2DGABBR2GABRR1GABBR1FDPS
SCHEMBL16208973 0.83 PLA2G2D (0.34) PLA2G2DGABBR2GABRR1GABBR1FDPS
SCHEMBL16163284 0.82 FDPS (0.44) PLA2G2DGABBR2GABRR1GABBR1FDPS
SCHEMBL16163412 0.82 LPAR3 (0.45) PLA2G2DGABBR2GABRR1GABBR1LPAR3
SCHEMBL16163129 0.81 LPAR3 (0.48) PLA2G2DFDPSLPAR3LPAR2
SCHEMBL16163200 0.74 GABBR2 (0.35) GCLCGABBR2GABBR1FDPSLAP3
SCHEMBL339643 0.73 FOLH1 (0.35) GCLCFDPSLAP3
SCHEMBL2513023 0.73 TRPM8 (0.46) GCLCGABBR2GABRR1GABBR1FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2791152-B1 MIXTURES OF DIPHOSPHINIC ACIDS AND DIALKYLPHOSPHINIC ACIDS, A PROCESS FOR THE PREPARATION THEREOF AND THE USE THEREOF CLARIANT INT LTD (CH) 2018-11-07 EP claimed
EP-2791149-B1 MIXTURES OF DIPHOSPHINIC ACIDS AND ALKYLPHOSPHINIC ACIDS, A PROCESS FOR THE PREPARATION THEREOF AND THE USE THEREOF CLARIANT INT LTD (CH) 2017-06-14 EP claimed
US-20150005421-A1 Mixtures Of Diphosphinic Acids And Dialkylphosphinic Acids, A Process For The Preparation Thereof And The Use Thereof CLARIANT FINANCE (BVI) LIMITED (VG) 2015-01-01 US claimed
US-20140329933-A1 Mixtures Of Diphosphinic Acids And Alkylphosphinic Acids, A Process For The Preparation Thereof And The Use Thereof CLARIANT INTERNATIONAL LTD. (CH) 2014-11-06 US claimed
US-20140309339-A1 Mixtures Of Diphosphinic Acids And Alkylphosphinic Acids, A Process For The Preparation Thereof And The Use Thereof CLARIANT FINANCE (BVI) LIMITED (VG) 2014-10-16 US claimed
US-20180030355-A1 Mixtures Of Diphosphinic Acids And Alkylphosphinic Acids, A Process For The Preparation Thereof And The Use Thereof CLARIANT INTERNATIONAL LTD. (CH) 2018-02-01 US disclosed
US-20170313942-A1 Mixtures Of Diphosphinic Acids And Dialkylphosphinic Acids, A Process For The Preparation Thereof And The Use Thereof CLARIANT INTERNATIONAL LTD. (CH) 2017-11-02 US disclosed
EP-2791149-B1 MIXTURES OF DIPHOSPHINIC ACIDS AND ALKYLPHOSPHINIC ACIDS, A PROCESS FOR THE PREPARATION THEREOF AND THE USE THEREOF CLARIANT INT LTD (CH) 2017-06-14 EP disclosed
US-20150005421-A1 Mixtures Of Diphosphinic Acids And Dialkylphosphinic Acids, A Process For The Preparation Thereof And The Use Thereof CLARIANT FINANCE (BVI) LIMITED (VG) 2015-01-01 US disclosed
US-20140329933-A1 Mixtures Of Diphosphinic Acids And Alkylphosphinic Acids, A Process For The Preparation Thereof And The Use Thereof CLARIANT INTERNATIONAL LTD. (CH) 2014-11-06 US disclosed
US-20140309339-A1 Mixtures Of Diphosphinic Acids And Alkylphosphinic Acids, A Process For The Preparation Thereof And The Use Thereof CLARIANT FINANCE (BVI) LIMITED (VG) 2014-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180030355-A1 Mixtures Of Diphosphinic Acids And Alkylphosphinic Acids, A Process For The Preparation Thereof And The Use Thereof PHOSPHO1, ENPP2, INPPL1 GCLC 3623/4885PLA2G2D 82/4885GABBR2 2790/4885
US-20170313942-A1 Mixtures Of Diphosphinic Acids And Dialkylphosphinic Acids, A Process For The Preparation Thereof And The Use Thereof C3AR1, DCPS, ENPP2 GCLC 3876/4885PLA2G2D 255/4885GABBR2 2368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.