SCHEMBL16163145

SCHEMBL16163145

O=C(O)C1Nc2ccccc2C1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.43
TSHR P16473 1/20 0.43
TNKS2 Q9H2K2 1/20 0.43
MAPT P10636 5/20 0.42
GAA P10253 1/20 0.42
ALOX15 P16050 1/20 0.41
HTT P42858 1/20 0.41
HBB P68871 1/20 0.41
EDNRB P24530 1/20 0.39
EDNRA P25101 1/20 0.39
KMT2A Q03164 3/20 0.39
ALDH1A1 P00352 3/20 0.39
MEN1 O00255 2/20 0.38
ADORA3 P0DMS8 1/20 0.38
THRB P10828 1/20 0.38
CHRM1 P11229 1/20 0.38
TBXA2R P21731 1/20 0.38
PTGS1 P23219 1/20 0.38
ADRA1A P35348 1/20 0.38
MAPK1 P28482 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3030100 0.89 MAOA (0.42) LMNATSHRTNKS2MAPTGAA
SCHEMBL8585951 0.82 MAPT (0.44) LMNATSHRTNKS2MAPTALOX15
SCHEMBL125094 0.82 MAPT (0.44) LMNATSHRTNKS2MAPTALOX15
SCHEMBL22722361 0.74 CREBBP (0.53) TSHRMAPTGAAALOX15HTT
SCHEMBL9744897 0.74 CREBBP (0.41) LMNATSHRTNKS2MAPTGAA
SCHEMBL31739367 0.72 TSHR (0.47) LMNATSHRTNKS2GAAKMT2A
SCHEMBL19492450 0.72 TSHR (0.47) LMNATSHRTNKS2GAAKMT2A
SCHEMBL8143860 0.72 TNKS2 (0.56) TSHRTNKS2MAPTGAAKMT2A
SCHEMBL6684295 0.72 MAPT (0.46) LMNAMAPTALOX15HTTHBB
SCHEMBL19568178 0.72 TSHR (0.50) LMNATSHRTNKS2GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020015839-A1 PROCESS AND APPARATUS FOR DYEING TEXTILES SANKO TEKSTIL ISLETMELERI SAN. VE TIC. A.S. (TR) 2020-01-23 WO disclosed
US-9145364-B2 Synthesis of psuedo indoxyl derivatives COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-09-29 US disclosed
US-20140309434-A1 SYNTHESIS OF PSUEDO INDOXYL DERIVATIVES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2014-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140309434-A1 SYNTHESIS OF PSUEDO INDOXYL DERIVATIVES IPO4, IPO11, IDO2 LMNA 3364/4885TSHR 4748/4885TNKS2 922/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.