SCHEMBL1616362

SCHEMBL1616362

O=C(O)C/C=C/c1ccc(O)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAM P19021 1/20 0.70
AKR1B10 O60218 3/20 0.55
AKR1B1 P15121 3/20 0.55
CA12 O43570 3/20 0.55
CA7 P43166 3/20 0.55
CA9 Q16790 3/20 0.55
CA14 Q9ULX7 3/20 0.55
TYR P14679 2/20 0.55
PKM P14618 2/20 0.55
CA4 P22748 2/20 0.55
CA6 P23280 2/20 0.55
CA5A P35218 2/20 0.55
CA5B Q9Y2D0 2/20 0.55
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
ESR1 P03372 1/20 0.55
CA3 P07451 1/20 0.55
DPP4 P27487 1/20 0.55
HCAR2 Q8TDS4 1/20 0.55
ESR2 Q92731 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9502575 1.00 PAM (0.70) PAMAKR1B10AKR1B1CA12CA7
SCHEMBL11042697 0.85 AKR1B10 (0.55) PAMAKR1B10AKR1B1CA12CA7
SCHEMBL2148302 0.83 PAM (1.00) PAMHCAR2MAOBF3CYP2D6
SCHEMBL156767 0.83 PAM (1.00) PAMHCAR2MAOBF3CYP2D6
SCHEMBL582727 0.83 PAM (1.00) PAMHCAR2MAOBF3CYP2D6
SCHEMBL25241811 0.82 PAM (0.68) PAMESR1ESR2MAOBCYP2D6
SCHEMBL9044093 0.82 PAM (0.68) PAMCA1MAOBCYP3A4RAB9A
SCHEMBL9161835 0.82 PAM (0.68) PAMMAOBCYP2D6CYP3A4NFKB1
SCHEMBL9046738 0.82 PAM (0.68) PAMMAOBALDH1A1MAPT
SCHEMBL9161849 0.82 PAM (0.68) PAMMAOBCYP2D6CYP3A4NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117510397-A Styrene acetate compound and preparation method and application thereof 青海大学 2024-02-06 CN disclosed
US-20220211796-A1 PEPTIDE ANTIBIOTICS AND METHODS OF USE THEREOF TRUSTEES OF TUFTS COLLEGE 2022-07-07 US disclosed
WO-2020232407-A9 PEPTIDE ANTIBIOTICS AND METHODS OF USE THEREOF TRUSTEES OF TUFTS COLLEGE (US) 2021-02-04 WO disclosed
WO-2020232407-A1 PEPTIDE ANTIBIOTICS AND METHODS OF USE THEREOF TRUSTEES OF TUFTS COLLEGE (US) 2020-11-19 WO disclosed
US-7923578-B2 Prevent sagging of skin; luster ; amidation of 3-(4-hydroxyphenyl)propionic acid with ammonia using 4-nitrophenol in ethyl acetateand dicyclohexylcarbodiimide; stirring ; precipitation dicyclohexylurea; filtration under vacuum INSTYTUT CHEMII BIOORGANICZNEJ PAN (PL) 2011-04-12 US disclosed
US-20090191118-A1 Cytotoxicity mediation of cells evidencing surface expression of TROP-2 ARIUS RESEARCH INC. 2009-07-30 US disclosed
EP-1841795-A4 CYTOTOXICITY MEDIATION OF CELLS EVIDENCING SURFACE EXPRESSION OF CD63 ARIUS RES INC (CA) 2009-05-06 EP disclosed
US-20090053215-A1 Cytotoxicity mediation of cells evidencing surface expression of CD63 ARIUS RESEARCH INC. (CA) 2009-02-26 US disclosed
EP-1996700-A1 CANCEROUS DISEASE MODIFYING ANTIBODY 141205-05 Arius Research Inc. (CA) 2008-12-03 EP disclosed
US-20080249334-A1 Method of Manufacturing 3-(4-Hydroxyphenyl)Propanoic Acid Amide, Its Application in the Manufacture of Anti-Aging Compositions and Anti-Aging Composition INSTYTUT CHEMII BIOORGANICZNEJ PAN (PL) 2008-10-09 US disclosed
WO-2007095748-A1 CANCEROUS DISEASE MODIFYING ANTIBODY 141205-05 ARIUS RESEARCH INC. (CA) 2007-08-30 WO disclosed
US-20070202113-A1 Cytotoxicity mediation of cells evidencing surface expression of TROP-2 ARIUS RESEARCH, INC. 2007-08-30 US disclosed
CN-1960756-A Cell-mediated cytotoxicity (CD 63) demonstration of cell membrane surface expression ARIUS RES INC (CA) 2007-05-09 CN disclosed
WO-2007046721-A2 A METHOD OF MANUFACTURING 3-(4-HYDROXYPHENYL)PROPANOIC ACID AMIDE, ITS APPLICATION IN THE MANUFACTURE OF ANTI-AGING COMPOSITIONS AND AN ANTI-AGING COMPOSITION INSTYTUT CHEMII BIOORGANICZNEJ PAN (PL) 2007-04-26 WO disclosed
WO-2005092377-A9 CYTOTOXICITY MEDIATION OF CELLS EVIDENCING SURFACE EXPRESSION OF CD63 ARIUS RES INC (CA) 2007-03-22 WO disclosed
EP-1732603-A1 CYTOTOXICITY MEDIATION OF CELLS EVIDENCING SURFACE EXPRESSION OF CD63 Arius Research, Inc. (CA) 2006-12-20 EP disclosed
US-20060204497-A1 Cytotoxicity mediation of cells evidencing surface expression of CD63 ARIUS RESEARCH INC (CA) 2006-09-14 US disclosed
WO-2006072166-A1 CYTOTOXICITY MEDIATION OF CELLS EVIDENCING SURFACE EXPRESSION OF CD63 ARIUS RESEARCH, INC. (CA) 2006-07-13 WO disclosed
WO-2005092377-A1 CYTOTOXICITY MEDIATION OF CELLS EVIDENCING SURFACE EXPRESSION OF CD63 ARIUS RESEARCH, INC. (CA) 2005-10-06 WO disclosed
US-20040258693-A1 Cytotoxicity mediation of cells evidencing surface expression of CD63 HOFFMAN-LA ROCHE INC. 2004-12-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220211796-A1 PEPTIDE ANTIBIOTICS AND METHODS OF USE THEREOF VIP, NGLY1, PEPD PAM 80/4885AKR1B10 4379/4885AKR1B1 4645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.