Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409678 | 0.91 | SMN1; SMN2 (0.54) | SMN1; SMN2NAPRTGRM4RAB9AMAPT | |
| SCHEMBL20372049 | 0.81 | HSD17B3 (0.54) | NAPRTGRM4RAB9AMAPTL3MBTL1 | |
| SCHEMBL1985578 | 0.81 | NAPRT (0.64) | SMN1; SMN2NAPRTGRM4RAB9AMAPT | |
| SCHEMBL2271956 | 0.80 | HSD17B3 (0.56) | NAPRTGRM4RAB9AMAPTL3MBTL1 | |
| SCHEMBL7467309 | 0.80 | TSHR (0.52) | RAB9AMAPTL3MBTL1NPC1ALDH1A1 | |
| SCHEMBL3299695 | 0.80 | NAPRT (0.55) | SMN1; SMN2NAPRTGRM4RAB9AMAPT | |
| SCHEMBL2270818 | 0.79 | HSD17B3 (0.57) | NAPRTGRM4RAB9AMAPTL3MBTL1 | |
| SCHEMBL13783888 | 0.78 | HDAC8 (0.46) | MAPTL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL11899972 | 0.78 | NAPRT (0.56) | SMN1; SMN2NAPRTGRM4RAB9AMAPT | |
| SCHEMBL12728201 | 0.77 | DGAT1 (0.59) | SMN1; SMN2NAPRTGRM4RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2984089-B1 | SUBSTITUTED PYRIMIDINIUM COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2022-03-09 | — | — | EP | disclosed |
| US-11019820-B2 | Substituted pyrimidinium compounds and derivatives for combating animal pests | BASF SE (DE) | 2021-06-01 | — | — | US | disclosed |
| US-20180007905-A1 | Substituted Pyrimidinium Compounds and Derivatives for Combating Animal Pests | BASF SE (DE) | 2018-01-11 | — | — | US | disclosed |
| US-9730451-B2 | Substituted pyrimidinium compounds and derivatives for combating animal pests | BASF SE (DE) | 2017-08-15 | — | — | US | disclosed |
| US-20160058009-A1 | Substituted Pyrimidinium Compounds and Derivatives for Combating Animal Pests | BASF SE (DE) | 2016-03-03 | — | — | US | disclosed |
| EP-2984089-A1 | SUBSTITUTED PYRIMIDINIUM COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2016-02-17 | — | — | EP | disclosed |
| WO-2014167084-A1 | SUBSTITUTED PYRIMIDINIUM COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2014-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160058009-A1 | Substituted Pyrimidinium Compounds and Derivatives for Combating Animal Pests | THOP1, PRDX2, PRDX1 | SMN1; SMN2 1373/4885NAPRT 446/4885GRM4 671/4885 |
| US-11019820-B2 | Substituted pyrimidinium compounds and derivatives for combating animal pests | THOP1, PRDX2, PRDX1 | SMN1; SMN2 1373/4885NAPRT 446/4885GRM4 671/4885 |
| US-20180007905-A1 | Substituted Pyrimidinium Compounds and Derivatives for Combating Animal Pests | THOP1, PRDX2, PRDX1 | SMN1; SMN2 1373/4885NAPRT 446/4885GRM4 671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.