Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1656241 | 0.66 | NFKB1 (0.41) | DRD2NFKB1NFKB2RELA | |
| SCHEMBL10512058 | 0.66 | NFKB1 (0.35) | DRD2NFKB1NFKB2RELALIPE | |
| SCHEMBL31363878 | 0.65 | DRD2 (0.36) | DRD2NFKB1NFKB2RELALIPE | |
| SCHEMBL573575 | 0.63 | NFKB1 (0.39) | NFKB1NFKB2RELA | |
| SCHEMBL1829582 | 0.63 | CYP17A1 (0.39) | DRD2NFKB1NFKB2RELA | |
| SCHEMBL30817405 | 0.63 | MAPT (0.50) | DRD2NFKB1NFKB2RELALIPE | |
| SCHEMBL30889135 | 0.63 | GAA (0.48) | DRD2NFKB1NFKB2RELA | |
| SCHEMBL21214308 | 0.63 | DRD2 (0.55) | DRD2L3MBTL1SIGMAR1CD274 | |
| SCHEMBL21395197 | 0.63 | RAB9A (0.36) | DRD2NFKB1NFKB2RELAL3MBTL1 | |
| SCHEMBL27673939 | 0.63 | PSMB8 (0.38) | NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160067162-A1 | PHOTOPROTECTIVE COMPOUNDS, COMPOSITIONS INCLUDING SAME AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) | 2016-03-10 | — | — | US | claimed |
| US-20160067162-A1 | PHOTOPROTECTIVE COMPOUNDS, COMPOSITIONS INCLUDING SAME AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) | 2016-03-10 | — | — | US | disclosed |
| US-20160067162-A1 | PHOTOPROTECTIVE COMPOUNDS, COMPOSITIONS INCLUDING SAME AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) | 2016-03-10 | — | — | US | disclosed |
| EP-2984071-A1 | PHOTOPROTECTIVE COMPOUNDS, COMPOSITIONS INCLUDING SAME AND USES THEREOF | Université de Rennes I (FR) | 2016-02-17 | — | — | EP | disclosed |
| WO-2014167225-A1 | PHOTOPROTECTIVE COMPOUNDS, COMPOSITIONS INCLUDING SAME AND USES THEREOF | UNIVERSITE DE RENNES 1 (FR) | 2014-10-16 | — | — | WO | disclosed |
| WO-2014167225-A1 | PHOTOPROTECTIVE COMPOUNDS, COMPOSITIONS INCLUDING SAME AND USES THEREOF | UNIVERSITE DE RENNES 1 (FR) | 2014-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160067162-A1 | PHOTOPROTECTIVE COMPOUNDS, COMPOSITIONS INCLUDING SAME AND USES THEREOF | CBR3, CBR1, C9 | DRD2 510/4885NFKB1 1146/4885NFKB2 1174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.