Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16166641 | 0.65 | DRD2 (0.38) | DRD2GSK3BDYRK1ANFKB1NFKB2 | |
| SCHEMBL21206288 | 0.64 | NFKB1 (0.35) | DRD2NFKB1NFKB2RELALIPE | |
| SCHEMBL31363590 | 0.64 | DRD2 (0.33) | DRD2GSK3BDYRK1ANFKB1NFKB2 | |
| SCHEMBL13055402 | 0.62 | CYP17A1 (0.59) | DRD2LIPENAMPTMAPKAPK2CA12 | |
| SCHEMBL1656241 | 0.62 | NFKB1 (0.41) | DRD2NFKB1NFKB2RELACA1 | |
| SCHEMBL27346938 | 0.62 | NFKB1 (0.36) | DRD2GSK3BDYRK1ANFKB1NFKB2 | |
| SCHEMBL3305574 | 0.62 | LIPE (0.36) | DRD2NFKB1NFKB2RELALIPE | |
| SCHEMBL17844767 | 0.62 | KMT2A (0.49) | GSK3BDYRK1ANAMPTCYP17A1ATR | |
| SCHEMBL35210874 | 0.62 | SMN1; SMN2 (0.57) | GSK3BDYRK1ACA12CA1CA9 | |
| SCHEMBL219325 | 0.62 | CYP17A1 (0.39) | DRD2GSK3BDYRK1ALIPENAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059074-A1 | BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |