Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11912033 | 0.90 | HDAC1 (0.54) | HDAC1HDAC2CASP3KMT2AIDO1 | |
| SCHEMBL31000548 | 0.90 | HDAC1 (0.54) | HDAC1HDAC2CASP3KMT2AIDO1 | |
| SCHEMBL29397673 | 0.90 | HDAC1 (0.54) | HDAC1HDAC2CASP3KMT2AIDO1 | |
| SCHEMBL28527138 | 0.90 | HDAC1 (0.54) | HDAC1HDAC2CASP3KMT2AIDO1 | |
| SCHEMBL13402442 | 0.90 | HDAC1 (0.54) | HDAC1HDAC2CASP3KMT2AIDO1 | |
| SCHEMBL30660213 | 0.88 | CASP3 (0.54) | CASP3KMT2A | |
| SCHEMBL11949183 | 0.88 | CASP3 (0.47) | CASP3KMT2A | |
| SCHEMBL9737331 | 0.88 | CASP3 (0.54) | CASP3KMT2A | |
| SCHEMBL23811018 | 0.87 | KMT2A (0.52) | CTSKHDAC1HDAC2CASP3KMT2A | |
| SCHEMBL17020412 | 0.85 | TLR2 (0.47) | CASP3KMT2ATNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8859730-B2 | Native chemical ligation at serine and threonine sites | SUZHOU NEXTIDE BIOTECH CO., LTD. (CN) | 2014-10-14 | — | — | US | disclosed |