Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 6/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | TNF | P01375 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31091386 | 0.92 | TLR2 (0.51) | TLR2CASP3TNFKMT2A | |
| SCHEMBL11949183 | 0.87 | CASP3 (0.47) | CASP3KMT2A | |
| SCHEMBL30954537 | 0.87 | TLR2 (0.49) | TLR2CASP3KMT2A | |
| SCHEMBL15186058 | 0.86 | CASP3 (0.48) | TLR2CASP3KMT2A | |
| SCHEMBL30660213 | 0.85 | CASP3 (0.54) | TLR2CASP3KMT2A | |
| SCHEMBL9737331 | 0.85 | CASP3 (0.54) | TLR2CASP3KMT2A | |
| SCHEMBL16167663 | 0.85 | CTSK (0.47) | CASP3TNFKMT2A | |
| SCHEMBL30229906 | 0.82 | TLR2 (0.51) | TLR2CASP3TNFKMT2A | |
| SCHEMBL16327986 | 0.82 | TLR2 (0.59) | TLR2TNF | |
| SCHEMBL29907904 | 0.81 | CASP3 (0.55) | TLR2CASP3TNFKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150232504-A1 | ALDEHYDE CAPTURE LIGATION TECHNOLOGY FOR SYNTHESIS OF AMIDE BONDS | NEW YORK UNIVERSITY (US) | 2015-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150232504-A1 | ALDEHYDE CAPTURE LIGATION TECHNOLOGY FOR SYNTHESIS OF AMIDE BONDS | ALDH3A1, ALDH2, ALDH1A1 | TLR2 2488/4885CASP3 3980/4885TNF 3823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.