Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22150338 | 0.74 | TRPA1 (0.46) | TRPA1TRPM8 | |
| SCHEMBL27950890 | 0.74 | TRPM8 (0.54) | TRPA1TRPM8 | |
| SCHEMBL9559604 | 0.74 | TRPA1 (0.42) | TRPA1TRPM8 | |
| SCHEMBL19920155 | 0.74 | TRPA1 (0.42) | TRPA1TRPM8 | |
| SCHEMBL19920235 | 0.74 | TRPA1 (0.42) | TRPA1TRPM8 | |
| SCHEMBL18105685 | 0.74 | TRPA1 (0.42) | TRPA1TRPM8 | |
| SCHEMBL18105686 | 0.74 | TRPA1 (0.42) | TRPA1TRPM8 | |
| SCHEMBL11677340 | 0.74 | TRPA1 (0.42) | TRPA1TRPM8 | |
| SCHEMBL18105741 | 0.74 | TRPA1 (0.42) | TRPA1TRPM8 | |
| SCHEMBL28409985 | 0.72 | TRPA1 (0.35) | TRPA1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761238-B1 | MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION COMPRISING THE SAME | TAKASAGO PERFUMERY CO LTD (JP) | 2012-09-05 | — | — | EP | disclosed |
| US-7923585-B2 | Menthol derivative and cooling agent composition comprising the same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-04-12 | — | — | US | disclosed |
| CN-1950057-B | Menthol derivative and cooling agent composition comprising the same | TAKASAGO PERFUMERY CO LTD | 2010-05-05 | — | — | CN | disclosed |
| US-20070225378-A1 | Menthol Dearivative and Cooling Agent Composition Comprising the Same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-09-27 | — | — | US | disclosed |
| CN-1950057-A | Menthol derivative and cooling agent composition comprising the same | TAKASAGO PERFUMERY CO LTD (JP) | 2007-04-18 | — | — | CN | disclosed |
| EP-1761238-A1 | MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION COMPRISING THE SAME | Takasago International Corporation (JP) | 2007-03-14 | — | — | EP | disclosed |
| WO-2005115325-A1 | MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION COMPRISING THE SAME | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2005-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225378-A1 | Menthol Dearivative and Cooling Agent Composition Comprising the Same | TRPM7, TRPA1, TRPM2 | TRPA1 2/4885TRPM8 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.