Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | ESRRB | O95718 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL825660 | 0.92 | ESR1 (0.44) | LMNAHSD17B10ESR1ESR2SYK | |
| SCHEMBL20348485 | 0.91 | ESR1 (0.35) | LMNAHSD17B10ESR1ESR2 | |
| SCHEMBL12965355 | 0.89 | TRPA1 (0.38) | LMNAHSD17B10ESR1ESR2PRKCA | |
| SCHEMBL2736414 | 0.83 | LMNA (0.39) | LMNAHSD17B10ESR1ESR2SYK | |
| SCHEMBL23434091 | 0.82 | MEN1 (0.43) | LMNACTSKCTSSMAPK1MEN1 | |
| SCHEMBL26374288 | 0.81 | LMNA (0.39) | LMNAHSD17B10ESR1ESR2SYK | |
| SCHEMBL14062409 | 0.80 | ATM (0.39) | LMNAHSD17B10PRKCAPRKCDCTSK | |
| SCHEMBL26080958 | 0.80 | ESR1 (0.42) | LMNAHSD17B10ESR1ESR2MAPT | |
| SCHEMBL16093070 | 0.79 | NPSR1 (0.40) | CTSKCTSSNPSR1MAPTMAPK1 | |
| SCHEMBL13813931 | 0.79 | UGT2B7 (0.41) | HSD17B10MEN1KMT2ACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140335455-A1 | UNDERLAYER COMPOSITION AND METHOD OF IMAGING UNDERLAYER COMPOSITION | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2014-11-13 | — | — | US | disclosed |
| US-20140335454-A1 | UNDERLAYER COMPOSITION AND METHOD OF IMAGING UNDERLAYER | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2014-11-13 | — | — | US | disclosed |
| US-8822133-B2 | Underlayer composition and method of imaging underlayer | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2014-09-02 | — | — | US | disclosed |
| US-8822124-B2 | Underlayer composition and method of imaging underlayer composition | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-09-02 | — | — | US | disclosed |
| US-20120088192-A1 | UNDERLAYER COMPOSITION AND METHOD OF IMAGING UNDERLAYER | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-04-12 | — | — | US | disclosed |
| US-20120088188-A1 | UNDERLAYER COMPOSITION AND METHOD OF IMAGING UNDERLAYER COMPOSITION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-04-12 | — | — | US | disclosed |