Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1617663 | 0.92 | LMNA (0.43) | ESR1ESR2LMNACYP1A2CYP2D6 | |
| SCHEMBL20348485 | 0.88 | ESR1 (0.35) | ESR1ESR2LMNACYP2C9CYP3A4 | |
| SCHEMBL26080958 | 0.86 | ESR1 (0.42) | ESR1ESR2LMNACYP2C9CHRM1 | |
| SCHEMBL14067005 | 0.84 | ESR1 (0.42) | ESR1ESR2APPPDCD1CD274 | |
| SCHEMBL12965355 | 0.83 | TRPA1 (0.38) | ESR1ESR2LMNACYP1A2CYP2D6 | |
| SCHEMBL13813931 | 0.80 | UGT2B7 (0.41) | CYP2C9SLC6A2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2736414 | 0.80 | LMNA (0.39) | ESR1ESR2LMNACHRM1CHRM2 | |
| SCHEMBL14996178 | 0.79 | ESR1 (0.51) | ESR1ESR2LMNACYP2C9CHRM1 | |
| SCHEMBL23434091 | 0.78 | MEN1 (0.43) | LMNASLC6A2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14066976 | 0.77 | NQO2 (0.35) | ESR1ESR2LMNACYP3A4ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180188648-A1 | RADIATION-SENSITIVE COMPOSITIONS AND PATTERNING AND METALLIZATION PROCESSES | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2018-07-05 | — | — | US | disclosed |
| US-9146467-B2 | Coating compositions | MERCK PATENT GMBH (DE) | 2015-09-29 | — | — | US | disclosed |
| US-20140335455-A1 | UNDERLAYER COMPOSITION AND METHOD OF IMAGING UNDERLAYER COMPOSITION | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2014-11-13 | — | — | US | disclosed |
| US-20140335454-A1 | UNDERLAYER COMPOSITION AND METHOD OF IMAGING UNDERLAYER | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2014-11-13 | — | — | US | disclosed |
| US-8822124-B2 | Underlayer composition and method of imaging underlayer composition | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-09-02 | — | — | US | disclosed |
| US-8822133-B2 | Underlayer composition and method of imaging underlayer | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2014-09-02 | — | — | US | disclosed |
| US-20130236833-A1 | COATING COMPOSITIONS | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2013-09-12 | — | — | US | disclosed |
| US-8455176-B2 | Coating composition | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2013-06-04 | — | — | US | disclosed |
| US-20120088192-A1 | UNDERLAYER COMPOSITION AND METHOD OF IMAGING UNDERLAYER | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-04-12 | — | — | US | disclosed |
| US-20120088188-A1 | UNDERLAYER COMPOSITION AND METHOD OF IMAGING UNDERLAYER COMPOSITION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-04-12 | — | — | US | disclosed |
| US-8142977-B2 | mixture of resin which decomposes under acid under exposure to actinic radiation, acid generator | FUJIFILM CORPORATION (JP) | 2012-03-27 | — | — | US | disclosed |
| US-8088548-B2 | Bottom antireflective coating compositions | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2012-01-03 | — | — | US | disclosed |
| US-20100119972-A1 | COATING COMPOSITION | MERCK PATENT GMBH (DE) | 2010-05-13 | — | — | US | disclosed |
| US-20090104559-A1 | Bottom Antireflective Coating Compositions | MERCK PATENT GMBH (DE) | 2009-04-23 | — | — | US | disclosed |
| US-20080241749-A1 | POSITIVE RESIST COMPOSITION AND PATTERN FORMING METHOD USING THE SAME | FUJIFILM CORPORATION (JP) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090104559-A1 | Bottom Antireflective Coating Compositions | SDC2, S100A9, MYH9 | ESR1 2135/4885ESR2 2409/4885LMNA 686/4885 |
| US-20100119972-A1 | COATING COMPOSITION | S100A9, CAPG, C5 | ESR1 2137/4885ESR2 1875/4885LMNA 603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.