Abrine

Abrine

SCHEMBL161767

CN[C@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.70
ACE P12821 3/20 0.69
KDM4E B2RXH2 2/20 0.68
MAPT P10636 2/20 0.68
APAF1 O14727 1/20 0.68
POLB P06746 1/20 0.68
RECQL P46063 1/20 0.68
L3MBTL1 Q9Y468 1/20 0.68
ITGB2 P05107 3/20 0.66
ICAM1 P05362 3/20 0.66
ITGAL P20701 3/20 0.66
SMN1; SMN2 Q16637 1/20 0.65
MEN1 O00255 1/20 0.63
LMNA P02545 1/20 0.63
MPO P05164 1/20 0.63
TSHR P16473 1/20 0.63
BLM P54132 1/20 0.63
PMP22 Q01453 1/20 0.63
KMT2A Q03164 1/20 0.63
HIF1A Q16665 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Abrine (L) SCHEMBL18777 1.00 ALOX15 (0.70) ALOX15ACEKDM4EMAPTAPAF1
Abrine SCHEMBL29404678 1.00 ALOX15 (0.70) ALOX15ACEKDM4EMAPTAPAF1
Abrine (L) SCHEMBL29585648 1.00 ALOX15 (0.70) ALOX15ACEKDM4EMAPTAPAF1
Abrine SCHEMBL18778 1.00 ALOX15 (0.70) ALOX15ACEKDM4EMAPTAPAF1
Abrine SCHEMBL23668057 0.99 ALOX15 (0.69) ALOX15ACEKDM4EMAPTAPAF1
Abrine SCHEMBL5056408 0.99 ALOX15 (0.69) ALOX15ACEKDM4EMAPTAPAF1
Abrine SCHEMBL8871893 0.99 ALOX15 (0.69) ALOX15ACEKDM4EMAPTAPAF1
Abrine SCHEMBL30320025 0.99 ALOX15 (0.69) ALOX15ACEKDM4EMAPTAPAF1
Abrine SCHEMBL30413313 0.99 ALOX15 (0.69) ALOX15ACEKDM4EMAPTAPAF1
Abrine (L) SCHEMBL5056403 0.99 ALOX15 (0.69) ALOX15ACEKDM4EMAPTAPAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8062 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122075573-A Application of herba abri total saponin extract in preparation of medicine for treating MAFLD 2026-05-26 CN claimed
WO-2026090266-A2 IONIZABLE LIPID PRODRUG COMPOUNDS AND LIPID NANOPARTICLES (LNPS) COMPRISING SAME THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2026-04-30 WO claimed
EP-3915587-B1 IMPROVED CELL-TARGETING BINDING MOLECULE SAPREME TECH BV (NL) 2026-03-25 EP claimed
US-20260049115-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER WITH ECM-AFFINITY PEPTIDES LINKED TO CYTOKINES THE UNIVERSITY OF CHICAGO (US) 2026-02-19 US claimed
US-12539338-B2 Nano-enabled immunotherapy in cancer THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-02-03 US claimed
US-12527872-B2 PEGylated ICD inducer-IDO inhibitor nanoconjugate, and preparation method and use thereof SHANDONG UNIVERSITY (CN) 2026-01-20 US claimed
EP-3897735-B1 BIOLOGICALLY ACTIVE CLUSTER OF MOLECULES SAPREME TECH BV (NL) 2025-10-22 EP claimed
CN-120154735-A Polyamino acid composite material, preparation method thereof and anti-tumor drug 中国科学院长春应用化学研究所 2025-06-17 CN claimed
US-12280047-B2 Treatment of aneurysms GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2025-04-22 US claimed
CN-115963203-B HPLC (high Performance liquid chromatography) characteristic spectrum construction method of abrus herb formula particles 四川新绿色药业科技发展有限公司 2025-03-25 CN claimed
EP-0981541-B1 PSCA: PROSTATE STEM CELL ANTIGEN UNIV CALIFORNIA (US) 2004-06-02 EP claimed
EP-0942972-B1 E25a PROTEIN, METHODS FOR PRODUCTION AND USE THEREOF UNIV CALIFORNIA (US) 2002-12-04 EP claimed
EP-1165134-A1 USE OF ANTI-FERRITIN MONOCLONAL ANTIBODIES IN THE TREATMENT OF SOME CANCERS Monoclonal Antibodies Therapeutics M.A.T. (FR) 2002-01-02 EP claimed
WO-2001052889-A1 USE OF ANTI-FERRITIN MONOCLONAL ANTIBODIES IN THE TREATMENT OF SOME CANCERS MONOCLONAL ANTIBODIES THERAPEUTICS 'M.A.T.' (FR) 2001-07-26 WO claimed
EP-0759087-B1 COMPOSITIONS AND METHODS FOR TARGETING GENE DELIVERY VEHICLES CHIRON CORP (US) 2001-03-28 EP claimed
EP-0597268-B1 Device and method of assaying whole blood for hdl cholesterol BAYER AG (US) 1999-05-06 EP claimed
US-5756650-A COMPOSITION COMPRISING POLYAMIC ACID, CURE ACCELERATOR SELECTED FROM GROUP CONSISTING OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, AMINO ACID COMPOUND, AROMATIC COMPOUND HAVING TWO OR MORE HYDROXYL GROUPS KABUSHIKI KAISHA TOSHIBA (JP) 1998-05-26 US claimed
EP-0295526-B1 PROCESS AND DEVICE FOR SEPARATING AND TESTING WHOLE BLOOD MILES INC. (US) 1992-04-22 EP claimed
US-5051351-A Sensitizers for silver halide emulsions EASTMAN KODAK COMPANY (US) 1991-09-24 US claimed
CN-88102026-A CHEMO-RADIO-IMMUNO-CONJUGATES 1988-09-28 CN claimed