Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | ACE | P12821 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | APAF1 | O14727 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.65 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.65 |
| ▸ | ITGAL | P20701 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | ECE1 | P42892 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MPO | P05164 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Abrine SCHEMBL8873731 | 1.00 | ALOX15 (0.69) | ALOX15ACEKDM4EMAPTAPAF1 | |
| Abrine SCHEMBL29404678 | 0.99 | ALOX15 (0.70) | ALOX15ACEKDM4EMAPTAPAF1 | |
| Abrine (L) SCHEMBL29585648 | 0.99 | ALOX15 (0.70) | ALOX15ACEKDM4EMAPTAPAF1 | |
| Abrine SCHEMBL18778 | 0.99 | ALOX15 (0.70) | ALOX15ACEKDM4EMAPTAPAF1 | |
| Abrine (L) SCHEMBL18777 | 0.99 | ALOX15 (0.70) | ALOX15ACEKDM4EMAPTAPAF1 | |
| Abrine SCHEMBL161767 | 0.99 | ALOX15 (0.70) | ALOX15ACEKDM4EMAPTAPAF1 | |
| Abrine SCHEMBL23668057 | 0.97 | ALOX15 (0.69) | ALOX15ACEKDM4EMAPTAPAF1 | |
| Abrine SCHEMBL5056408 | 0.97 | ALOX15 (0.69) | ALOX15ACEKDM4EMAPTAPAF1 | |
| Abrine SCHEMBL30320025 | 0.97 | ALOX15 (0.69) | ALOX15ACEKDM4EMAPTAPAF1 | |
| Abrine SCHEMBL30413313 | 0.97 | ALOX15 (0.69) | ALOX15ACEKDM4EMAPTAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610177-A | Acylated amino acids as endothelin antagonists | WARNER-LAMBERT COMPANY (US) | 1997-03-11 | — | — | US | disclosed |