Sugi Predict

Sugi Predict / Compounds / SCHEMBL1617870

SCHEMBL1617870

SCHEMBL1617870

CCCCCCCC/C=C/OC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FAAH O00519 4/20 0.50
▸ TRPV1 Q8NER1 1/20 0.50
▸ TSHR P16473 2/20 0.44
▸ TERT O14746 3/20 0.43
▸ CYP1A2 P05177 2/20 0.43
▸ MAPT P10636 2/20 0.43
▸ CYP2C19 P33261 2/20 0.43
▸ BLM P54132 2/20 0.43
▸ HSD17B10 Q99714 2/20 0.43
▸ FABP4 P15090 2/20 0.43
▸ PTPN1 P18031 2/20 0.43
▸ PPARG P37231 2/20 0.43
▸ KMT2A Q03164 2/20 0.43
▸ PPARD Q03181 2/20 0.43
▸ PPARA Q07869 2/20 0.43
▸ GMNN O75496 1/20 0.43
▸ USP2 O75604 1/20 0.43
▸ LMNA P02545 1/20 0.43
▸ POLB P06746 1/20 0.43
▸ CYP2C9 P11712 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1723664 1.00 FAAH (0.50) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL1723661 1.00 FAAH (0.50) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL18339650 1.00 FAAH (0.50) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL1142198 1.00 FAAH (0.50) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL539072 1.00 FAAH (0.50) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL539071 1.00 FAAH (0.50) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL1617871 1.00 FAAH (0.50) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL16588401 1.00 FAAH (0.50) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL21995855 1.00 FAAH (0.50) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL385959 1.00 FAAH (0.50) FAAHTRPV1TSHRTERTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7175871-B2 Acyclic enol ethers, isomers thereof, organoleptic uses thereof and processes for preparing same INTERNATIONAL FLAVORS & FRAGRANCES INC (US) 2007-02-13 — — US claimed
EP-0217581-A1 Carboxylate salt compound and method for flavouring foodstuffs and tobacco HERCULES INCORPORATED (US) 1987-04-08 — — EP claimed
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 — — US disclosed
US-11758933-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2023-09-19 — — US disclosed
EP-3368542-B1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2022-06-22 — — EP disclosed
US-11357246-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2022-06-14 — — US disclosed
US-20210227863-A1 HIGH INTENSITY SWEETENERS SENOMYX, INC. 2021-07-29 — — US disclosed
EP-3356356-B1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 FIRMENICH INCORPORATED (US) 2021-05-26 — — EP disclosed
US-10392371-B2 Compounds useful as modulators of TRPM8 SENOMYX, INC. (US) 2019-08-27 — — US disclosed
US-20190177308-A9 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 SENOMYX, INC. 2019-06-13 — — US disclosed
US-20180273517-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 SENOMYX INC (US) 2018-09-27 — — US disclosed
US-20040091595-A1 Fruit, berry, cranberry and hedonically-stable citrus flavored compositions and process for preparing same INTERNATIONAL FLAVORS & FRAGRANCES INC. 2004-05-13 — — US disclosed
EP-1417896-A1 Fruit, berry, cranberry and hedonically-stable citrus flavored compositions and process for preparing same INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2004-05-12 — — EP disclosed
US-20040013779-A1 Acyclic enol ethers, isomers thereof, organoleptic uses thereof and processes for preparing same MOOKHERJEE BRAJA DULAL (US) 2004-01-22 — — US disclosed
US-5767325-A Preparation of enol ethers BASF AKTIENGESELLSCHAFT (DE) 1998-06-16 — — US disclosed
EP-0776879-A1 Process for the preparation of enol ethers BASF AKTIENGESELLSCHAFT (DE) 1997-06-04 — — EP disclosed
US-5079023-A During consumption; beverages HERCULES INCORPORATED (US) 1992-01-07 — — US disclosed
US-4781762-A ALDEHYDE-RELEASING HERCULES INCORPORATED (US) 1988-11-01 — — US disclosed
US-4697025-A ETHERS WHICH DECOMPOSE TO ALDEHYDES HERCULES INCORPORATED (US) 1987-09-29 — — US disclosed
US-4280011-A FLAVORINGS HERCULES INCORPORATED (US) 1981-07-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108040-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 FAAH 2804/4885TRPV1 99/4885TSHR 3246/4885
US-10392371-B2 Compounds useful as modulators of TRPM8 TRPM8, TRPM4, TRPM6 FAAH 762/4885TRPV1 7/4885TSHR 2580/4885
US-11357246-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 FAAH 2804/4885TRPV1 99/4885TSHR 3246/4885
US-20190177308-A9 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 TRPM8, TRPM6, TRPM4 FAAH 705/4885TRPV1 7/4885TSHR 2031/4885
US-20180273517-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 TRPM8, TRPM6, TRPM4 FAAH 705/4885TRPV1 7/4885TSHR 2031/4885
US-20210227863-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 FAAH 2804/4885TRPV1 99/4885TSHR 3246/4885
US-11758933-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 FAAH 2804/4885TRPV1 99/4885TSHR 3246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.