SCHEMBL161791

SCHEMBL161791

Cc1ccc(CC(C)N)cc1C

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PNMT P11086 2/20 0.57
HTR2A P28223 1/20 0.55
HTR2C P28335 1/20 0.55
HTR2B P41595 1/20 0.55
TAAR1 Q96RJ0 5/20 0.52
SLC6A2 P23975 4/20 0.52
SLC6A3 Q01959 3/20 0.52
SLC6A4 P31645 2/20 0.50
MAOA P21397 1/20 0.50
SIGMAR1 Q99720 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13972055 1.00 PNMT (0.57) PNMTHTR2AHTR2CHTR2BTAAR1
SCHEMBL7562470 0.82 GABRA1 (0.50) HTR2AHTR2BSLC6A2SLC6A3
SCHEMBL892653 0.82 TAAR1 (0.57) PNMTHTR2AHTR2CHTR2BTAAR1
SCHEMBL14071835 0.82 PNMT (0.52) PNMTHTR2AHTR2CHTR2BTAAR1
SCHEMBL13248703 0.82 SLC6A2 (0.52) PNMTHTR2AHTR2CHTR2BTAAR1
SCHEMBL20079631 0.80 PNMT (0.50) PNMTHTR2AHTR2CHTR2BTAAR1
Hydrochloric Acid SCHEMBL11091077 0.80 TAAR1 (0.55) PNMTHTR2AHTR2CHTR2BTAAR1
Hydrochloric Acid SCHEMBL3118224 0.80 PNMT (0.50) PNMTHTR2AHTR2CHTR2BTAAR1
Hydrochloric Acid SCHEMBL3108070 0.80 SLC6A2 (0.50) PNMTHTR2AHTR2CHTR2BTAAR1
SCHEMBL28523195 0.79 SLC6A4 (0.38) PNMTHTR2AHTR2CHTR2BSLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112213412-A Method for detecting drug and metabolite thereof in hair 四川警察学院 2021-01-12 CN claimed
US-20200060997-A1 TARR Receptor Agonists for Sexual Dysfunction JOHN MCCOY 2020-02-27 US claimed
EP-3366306-A2 USE OF SOME PEPTIDES IN DIAGNOSIS AND TREATMENT OF DIABETES, OBESITY AND METABOLIC DISEASES ASSOCIATED THERETO Istanbul Universitesi Rektorlugu (TR) 2018-08-29 EP claimed
EP-3351262-A1 CURAGLUTIDE FOR IN TREATMENT OF PREDIABETES, DIABETES, OBESITY AND METABOLIC DISEASES ASSOCIATED THERETO Istanbul Universitesi Rektorlugu (TR) 2018-07-25 EP claimed
US-20160000815-A1 COMPOSITIONS AND METHODS FOR TREATING PSYCHIATRIC DISORDERS GOSFORTH CT HOLDINGS PTY LTD (AU) 2016-01-07 US claimed
CN-103615927-B Blower motor external valve water-cooling system cooling tower STATE GRID CORPORATION OF CHINA (CN) 2015-08-19 CN claimed
CN-103633740-B Telecontrol channel fault monitoring device STATE GRID CORPORATION OF CHINA (CN) 2015-08-19 CN claimed
CN-103434300-B Anti-fake bill allowing codes to be changeable ZHENGZHOU TUNGKONG SECURITY PRINTING CO LTD 2015-04-15 CN claimed
US-20140142140-A1 PHARMACEUTICAL COMPOSITION FOR NEUROLOGICAL DISORDERS GOSFORTH CENTRE (HOLDINGS) PTY LTD (AU) 2014-05-22 US claimed
EP-2729216-A1 PHARMACEUTICAL COMPOSITION FOR NEUROLOGICAL DISORDERS Gosforth Centre (Holdings) Pty Ltd (AU) 2014-05-14 EP claimed
WO-2013007698-A1 PHARMACEUTICAL COMPOSITION FOR NEUROLOGICAL DISORDERS GOSFORTH CENTRE (HOLDINGS) PTY LTD (AU) 2013-01-17 WO claimed
JP-2011529923-A 2011-12-15 JP claimed
CN-102170874-A Compositions and methods for treating psychiatric disorders GOSFORTH CT HOLDINGS PTY LTD 2011-08-31 CN claimed
US-20110207718-A1 COMPOSITIONS AND METHODS FOR TREATING PSYCHIATRIC DISORDERS GOSFORTH CENTRE (HOLDINGS) PTY LTD. (AU) 2011-08-25 US claimed
EP-2331088-A1 COMPOSITIONS AND METHODS FOR TREATING PSYCHIATRIC DISORDERS Gosforth Centre (Holdings) Pty Ltd (AU) 2011-06-15 EP claimed
US-20100172916-A1 SUBSTITUTED HYDROXYPHENYLAMINE COMPOUNDS AUSPEX PHARMACEUTICALS, INC. (US) 2010-07-08 US claimed
WO-2010015029-A1 COMPOSITIONS AND METHODS FOR TREATING PSYCHIATRIC DISORDERS GOSFORTH CENTRE (HOLDINGS) PTY LTD (AU) 2010-02-11 WO claimed
WO-2026106796-A1 SYSTEM AND METHOD FOR THE TREATMENT OF TELOGEN EFFLUVIUM, ANDROGENETIC ALOPECIA, AND OTHER HAIR LOSS DISORDERS FOLLEA INTERNATIONAL (US) 2026-05-21 WO disclosed
WO-2008095253-A1 TREATMENT OF ADHD GOSFORTH CENTRE (HOLDINGS) PTY LTD (AU) 2008-08-14 WO disclosed
US-20070027208-A1 Antiparkinsonian Action of Phenylisopropylamines NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070027208-A1 Antiparkinsonian Action of Phenylisopropylamines PNMT, SNCA, COMT PNMT 1/4885HTR2A 18/4885HTR2C 44/4885
US-20100172916-A1 SUBSTITUTED HYDROXYPHENYLAMINE COMPOUNDS MC1R, TYR, MITF PNMT 56/4885HTR2A 62/4885HTR2C 84/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.