Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.52 |
| ▸ | HINT1 | P49773 | 2/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
| ▸ | KRAS | P01116 | 11/20 | 0.49 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 2/20 | 0.47 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2691311 | 0.82 | HINT1 (0.54) | NT5EHINT1TGM2KRASFUT5 | |
| Guanosine SCHEMBL9238739 | 0.76 | NT5E (0.69) | NT5EHINT1TGM2KRASFUT5 | |
| Guanosine SCHEMBL21315718 | 0.76 | HPGD (0.71) | NT5EHINT1TGM2KRASGSK3A | |
| Guanosine SCHEMBL31361372 | 0.76 | NT5E (0.72) | NT5EHINT1TGM2KRASFUT5 | |
| Guanosine SCHEMBL1304255 | 0.76 | NT5E (0.72) | NT5EHINT1TGM2KRASFUT5 | |
| Guanosine SCHEMBL2589323 | 0.76 | NT5E (0.72) | NT5EHINT1TGM2KRASFUT5 | |
| Guanosine SCHEMBL94793 | 0.76 | NT5E (0.72) | NT5EHINT1TGM2KRASFUT5 | |
| Guanosine SCHEMBL44407 | 0.76 | NT5E (0.72) | NT5EHINT1TGM2KRASFUT5 | |
| Guanosine SCHEMBL376138 | 0.76 | NT5E (0.72) | NT5EHINT1TGM2KRASFUT5 | |
| Guanosine SCHEMBL5356557 | 0.75 | NT5E (0.70) | NT5EHINT1TGM2KRASFUT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424874-A1 | NOVEL PHOSPHATE MODIFIED NUCLEOSIDES USEFUL AS SUBSTRATES FOR POLYMERASES AND AS ANTIVIRAL ANGENTS | Katholieke Universiteit Leuven, K.U. Leuven R&D (BE) | 2012-03-07 | — | — | EP | disclosed |