SCHEMBL1618282

SCHEMBL1618282

CCOc1c(O)cccc1F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.42
GAA P10253 4/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA12 O43570 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
ALDH1A1 P00352 6/20 0.41
KDM4E B2RXH2 5/20 0.41
MAPT P10636 3/20 0.41
HPGD P15428 2/20 0.41
HSD17B10 Q99714 2/20 0.41
GLA P06280 1/20 0.41
LMNA P02545 4/20 0.36
SMN1; SMN2 Q16637 4/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
TDP1 Q9NUW8 1/20 0.36
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1547887 0.85 L3MBTL1 (0.48) L3MBTL1GAAALDH1A1KDM4ELMNA
SCHEMBL2319403 0.85 CA1 (0.48) GAACA1CA2CA12CA7
SCHEMBL12648400 0.83 CCNB2 (0.42) L3MBTL1ALDH1A1MAPTLMNAMEN1
SCHEMBL29234053 0.82 NR5A1 (0.43) L3MBTL1ALDH1A1MAPTMEN1KMT2A
SCHEMBL30417451 0.81 BACE1 (0.44) L3MBTL1GAACA1CA2CA12
SCHEMBL29234061 0.80 NR5A1 (0.46) L3MBTL1ALDH1A1MAPTMEN1KMT2A
SCHEMBL16954649 0.79 L3MBTL1 (0.39) L3MBTL1GAAALDH1A1KDM4ELMNA
SCHEMBL8072909 0.78 ALDH1A1 (0.49) GAACA1CA2CA12CA7
SCHEMBL3329675 0.78 L3MBTL1 (0.49) L3MBTL1GAACA1CA2CA12
SCHEMBL13696460 0.78 ACHE (0.44) L3MBTL1KDM4ELMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7928268-B2 Process for producing 1,2-dialkoxy-3-fluorobenzene ASAHI GLASS COMPANY, LIMITED (JP) 2011-04-19 US claimed
US-20100286451-A1 Process for producing 1,2-dialkoxy-3-fluorobenzene ASAHI GLASS COMPANY, LIMITED 2010-11-11 US claimed
US-20090227817-A1 Process for producing 1,2-dialkoxy-3-fluorobenzene ASAHI GLASS COMPANY, LIMITED 2009-09-10 US claimed
EP-2055692-A1 PROCESS FOR PRODUCING 1,2-DIALKOXY-3-FLUOROBENZENE Asahi Glass Co., Ltd. (JP) 2009-05-06 EP claimed
WO-2011064789-A1 IMPROVED PROCESS FOR THE PREPARATION OF HALO-DIALKOXYBENZENES HIKAL LIMITED (IN) 2011-06-03 WO disclosed
US-7928268-B2 Process for producing 1,2-dialkoxy-3-fluorobenzene ASAHI GLASS COMPANY, LIMITED (JP) 2011-04-19 US disclosed
US-7928268-B2 Process for producing 1,2-dialkoxy-3-fluorobenzene ASAHI GLASS COMPANY, LIMITED (JP) 2011-04-19 US disclosed
US-7928268-B2 Process for producing 1,2-dialkoxy-3-fluorobenzene ASAHI GLASS COMPANY, LIMITED (JP) 2011-04-19 US disclosed
US-20100286451-A1 Process for producing 1,2-dialkoxy-3-fluorobenzene ASAHI GLASS COMPANY, LIMITED 2010-11-11 US disclosed
US-20100286451-A1 Process for producing 1,2-dialkoxy-3-fluorobenzene ASAHI GLASS COMPANY, LIMITED 2010-11-11 US disclosed
US-20100286451-A1 Process for producing 1,2-dialkoxy-3-fluorobenzene ASAHI GLASS COMPANY, LIMITED 2010-11-11 US disclosed
US-7786330-B2 sulfonation, halogenation, deprotection, with 2-fluorophenol as starting material; industrial scale ASAHI GLASS COMPANY, LIMITED (JP) 2010-08-31 US disclosed
US-7786330-B2 sulfonation, halogenation, deprotection, with 2-fluorophenol as starting material; industrial scale ASAHI GLASS COMPANY, LIMITED (JP) 2010-08-31 US disclosed
US-20090227817-A1 Process for producing 1,2-dialkoxy-3-fluorobenzene ASAHI GLASS COMPANY, LIMITED 2009-09-10 US disclosed
US-20090227817-A1 Process for producing 1,2-dialkoxy-3-fluorobenzene ASAHI GLASS COMPANY, LIMITED 2009-09-10 US disclosed
EP-2055692-A1 PROCESS FOR PRODUCING 1,2-DIALKOXY-3-FLUOROBENZENE Asahi Glass Co., Ltd. (JP) 2009-05-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090227817-A1 Process for producing 1,2-dialkoxy-3-fluorobenzene HAAO, HDHD5, AFF2 L3MBTL1 2854/4885GAA 2948/4885CA1 2582/4885
US-20100286451-A1 Process for producing 1,2-dialkoxy-3-fluorobenzene HAAO, HDHD5, AFF2 L3MBTL1 2854/4885GAA 2948/4885CA1 2582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.