Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 6/20 | 0.68 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.68 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.68 |
| ▸ | UQCRB | P14927 | 3/20 | 0.65 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16187961 | 0.86 | UQCRB (0.64) | HSD17B2PTPN5UQCRBCA1CA2 | |
| SCHEMBL17849569 | 0.84 | MAPT (0.58) | HSD17B2PTPN5UQCRBCA1CA2 | |
| SCHEMBL10013443 | 0.83 | PTPN5 (0.68) | HSD17B2PTPN5UQCRBCA1CA2 | |
| SCHEMBL208685 | 0.82 | UQCRB (0.67) | HSD17B2PTPN5UQCRBCA1CA2 | |
| SCHEMBL17849562 | 0.81 | HSD17B2 (0.58) | HSD17B2UQCRBCA1CA2MEN1 | |
| SCHEMBL15121254 | 0.81 | PTPN5 (1.00) | HSD17B2PTPN5UQCRBCA1CA2 | |
| SCHEMBL7523467 | 0.81 | HSD17B3 (0.73) | HSD17B2HSD17B3CA1CA2HSP90AA1 | |
| SCHEMBL812679 | 0.80 | ALDH1A1 (0.83) | PTPN5UQCRBCA1CA2MEN1 | |
| SCHEMBL7178237 | 0.79 | UQCRB (1.00) | HSD17B2PTPN5UQCRBCA1CA2 | |
| SCHEMBL19281326 | 0.78 | PTPN5 (0.81) | PTPN5UQCRBCA1CA2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9371286-B2 | Pharmaceutical composition with enhanced efficacy for inhibiting angiogenesis | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2016-06-21 | — | — | US | disclosed |
| US-9371286-B2 | Pharmaceutical composition with enhanced efficacy for inhibiting angiogenesis | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2016-06-21 | — | — | US | disclosed |
| US-20140315947-A1 | PHARMACEUTICAL COMPOSITION WITH ENHANCED EFFICACY FOR INHIBITING ANGIOGENESIS | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2014-10-23 | — | — | US | disclosed |
| US-20140315947-A1 | PHARMACEUTICAL COMPOSITION WITH ENHANCED EFFICACY FOR INHIBITING ANGIOGENESIS | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2014-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140315947-A1 | PHARMACEUTICAL COMPOSITION WITH ENHANCED EFFICACY FOR INHIBITING ANGIOGENESIS | UQCRB, UQCRC1, UQCRC2 | HSD17B2 3640/4885HSD17B3 3047/4885PTPN5 1951/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.