Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | UQCRB | P14927 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | RORA | P35398 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | IKBKB | O14920 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16187961 | 0.87 | UQCRB (0.64) | HSD17B2ALDH1A1UQCRBCA1CA2 | |
| SCHEMBL17849569 | 0.85 | MAPT (0.58) | HSD17B2ALDH1A1UQCRBCA1CA2 | |
| SCHEMBL16187970 | 0.81 | HSD17B2 (0.68) | HSD17B2ALDH1A1UQCRBCA1CA2 | |
| SCHEMBL812679 | 0.80 | ALDH1A1 (0.83) | ALDH1A1UQCRBCA1CA2MEN1 | |
| SCHEMBL17849560 | 0.79 | GAA (0.59) | ALDH1A1UQCRBCA1CA2MEN1 | |
| SCHEMBL29561330 | 0.78 | MAPT (0.61) | HSD17B2ALDH1A1UQCRBCA1CA2 | |
| SCHEMBL1040954 | 0.78 | ALDH1A1 (0.73) | HSD17B2ALDH1A1UQCRBCA1CA2 | |
| SCHEMBL13433558 | 0.78 | ALDH1A1 (0.73) | HSD17B2ALDH1A1UQCRBCA1CA2 | |
| SCHEMBL30230090 | 0.77 | FFAR1 (0.63) | ALDH1A1UQCRBCA1CA2MEN1 | |
| SCHEMBL17849567 | 0.76 | UQCRB (0.72) | HSD17B2ALDH1A1UQCRBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9371286-B2 | Pharmaceutical composition with enhanced efficacy for inhibiting angiogenesis | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2016-06-21 | — | — | US | disclosed |